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Interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin

The interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin was studied by equilibrium dialysis. A 20-fold variation of buffer ionic strength (0.017-0.340) caused no significant change in the warfarin association constant. But the binding strength rose significan...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Glavni avtor: O'Reilly, Robert A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1969
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5765021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105968
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