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Amiodarone reduces plasma warfarin clearance in man.

Amiodarone is an effective antiarrhythmic agent whose use is associated with several drug interactions one of which is potentiation of the action of warfarin. The mechanism of this interaction has hitherto been unclear. We examined possible mechanisms in eight patients. Total plasma warfarin clearan...

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Autors principals: Watt, A H, Stephens, M R, Buss, D C, Routledge, P A
Format: Artigo
Idioma:Inglês
Publicat: 1985
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400826/
https://ncbi.nlm.nih.gov/pubmed/4092002
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