The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the Neurotensin receptor type 2

Por Thomas, James B., Giddings, Angela M., Olepu, Srinivas, Wiethe, Robert W., Warner, Keith R., Sarret, Philippe, Longpre, Jean-Michel, Runyon, Scott P., Gilmour, Brian P
Publicado no Bioorg Med Chem Lett (2015)

Identification of N-[(5-{[(4-Methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a Neurotensin-like Nonpeptide Compound Selective for the N...

Por Thomas, James B., Giddings, Angela M., Wiethe, Robert W., Olepu, Srinivas, Warner, Keith R., Sarret, Philippe, Gendron, Louis, Longpre, Jean-Michel, Zhang, Yanan, Runyon, Scott P., Gilmour, Brian P.
Publicado em 2014

Identification of 1-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compo...

Por Thomas, James B., Giddings, Angela M., Wiethe, Robert W., Olepu, Srinivas, Warner, Keith R., Sarret, Philippe, Gendron, Louis, Longpre, Jean-Michel, Zhang, Yanan, Runyon, Scott P., Gilmour, Brian P.
Publicado no J Med Chem (2014)

Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-L-leucine (NTRC-808), a novel nonpeptide chemotype selective for the Neurotensin receptor type 2

Por Thomas, James B., Giddings, Angela M., Olepu, Srinivas, Wiethe, Robert W., Harris, Danni L., Narayanan, Sanju, Warner, Keith R., Sarret, Philippe, Longpre, Jean-Michel, Runyon, Scott P., Gilmour, Brian P.
Publicado no Bioorg Med Chem Lett (2014)