Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

per Ferron, Laurent, Nieto-Rostro, Manuela, Cassidy, John S., Dolphin, Annette C.
Publicat 2014

Effect of knockout of α(2)δ-1 on action potentials in mouse sensory neurons

per Margas, Wojciech, Ferron, Laurent, Nieto-Rostro, Manuela, Schwartz, Arnold, Dolphin, Annette C.
Publicat a Philos Trans R Soc Lond B Biol Sci (2016)

Ablation of α(2)δ-1 inhibits cell-surface trafficking of endogenous N-type calcium channels in the pain pathway in vivo

per Nieto-Rostro, Manuela, Ramgoolam, Krishma, Pratt, Wendy S., Kulik, Akos, Dolphin, Annette C.
Publicat a Proc Natl Acad Sci U S A (2018)

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α(2)δ-1 subunit

per Kadurin, Ivan, Rothwell, Simon W., Lana, Beatrice, Nieto-Rostro, Manuela, Dolphin, Annette C.
Publicat a Sci Rep (2017)

Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α(2)δ-1-subunit but does not interact with α(2)δ-1 on the cell-surface when co-expressed

per Lana, Beatrice, Page, Karen M., Kadurin, Ivan, Ho, Shuxian, Nieto-Rostro, Manuela, Dolphin, Annette C.
Publicat a Sci Rep (2016)

A Ca(V)2.1 N-terminal fragment relieves the dominant-negative inhibition by an Episodic ataxia 2 mutant

per Dahimene, Shehrazade, Page, Karen M., Nieto-Rostro, Manuela, Pratt, Wendy S., D'Arco, Marianna, Dolphin, Annette C.
Publicat a Neurobiol Dis (2016)

Interaction via a Key Tryptophan in the I-II Linker of N-Type Calcium Channels Is Required for β1 But Not for Palmitoylated β2, Implicating an Additional Binding Site in the Regula...

per Leroy, Jérôme, Richards, Mark S., Butcher, Adrian J., Nieto-Rostro, Manuela, Pratt, Wendy S., Davies, Anthony, Dolphin, Annette C.
Publicat a J Neurosci (2005)

The α(2)δ subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function

per Davies, Anthony, Kadurin, Ivan, Alvarez-Laviada, Anita, Douglas, Leon, Nieto-Rostro, Manuela, Bauer, Claudia S., Pratt, Wendy S., Dolphin, Annette C.
Publicat 2010

N Terminus Is Key to the Dominant Negative Suppression of Ca(V)2 Calcium Channels: IMPLICATIONS FOR EPISODIC ATAXIA TYPE 2

per Page, Karen M., Heblich, Fay, Margas, Wojciech, Pratt, Wendy S., Nieto-Rostro, Manuela, Chaggar, Kanchan, Sandhu, Kieran, Davies, Anthony, Dolphin, Annette C.
Publicat 2010

Pharmacological disruption of calcium channel trafficking by the α(2)δ ligand gabapentin

per Hendrich, Jan, Van Minh, Alexandra Tran, Heblich, Fay, Nieto-Rostro, Manuela, Watschinger, Katrin, Striessnig, Jörg, Wratten, Jack, Davies, Anthony, Dolphin, Annette C.
Publicat 2008

The ducky(2J) Mutation in Cacna2d2 Results in Reduced Spontaneous Purkinje Cell Activity and Altered Gene Expression

per Donato, Roberta, Page, Karen M., Koch, Dietlind, Nieto-Rostro, Manuela, Foucault, Isabelle, Davies, Anthony, Wilkinson, Tonia, Rees, Michele, Edwards, Frances A., Dolphin, Annette C.
Publicat 2006

Proteolytic maturation of α(2)δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels

per Kadurin, Ivan, Ferron, Laurent, Rothwell, Simon W, Meyer, James O, Douglas, Leon R, Bauer, Claudia S, Lana, Beatrice, Margas, Wojciech, Alexopoulos, Orpheas, Nieto-Rostro, Manuela, Pratt, Wendy S, Dolphin, Annette C
Publicat a eLife (2016)

α(2)δ-1 Gene Deletion Affects Somatosensory Neuron Function and Delays Mechanical Hypersensitivity in Response to Peripheral Nerve Damage

per Patel, Ryan, Bauer, Claudia S., Nieto-Rostro, Manuela, Margas, Wojciech, Ferron, Laurent, Chaggar, Kanchan, Crews, Kasumi, Ramirez, Juan D., Bennett, David L. H., Schwartz, Arnold, Dickenson, Anthony H., Dolphin, Annette C.
Publicat 2013

The Increased Trafficking of the Calcium Channel Subunit α(2)δ-1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the α(2)δ Ligand Pregabalin

per Bauer, Claudia S., Nieto-Rostro, Manuela, Rahman, Wahida, Tran-Van-Minh, Alexandra, Ferron, Laurent, Douglas, Leon, Kadurin, Ivan, Sri Ranjan, Yorain, Fernandez-Alacid, Laura, Millar, Neil S., Dickenson, Anthony H., Lujan, Rafael, Dolphin, Annette C.
Publicat a J Neurosci (2009)