A carregar...
Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α(2)δ-1-subunit but does not interact with α(2)δ-1 on the cell-surface when co-expressed
The α(2)δ proteins are auxiliary subunits of voltage-gated calcium channels, and influence their trafficking and biophysical properties. The α(2)δ ligand gabapentin interacts with α(2)δ-1, and inhibits calcium channel trafficking. However, α(2)-1 has also been proposed to play a synaptogenic role, i...
Na minha lista:
Publicado no: | Sci Rep |
---|---|
Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
|
Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4830977/ https://ncbi.nlm.nih.gov/pubmed/27076051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24531 |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|