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The α(2)δ Ligand Gabapentin Inhibits the Rab11-Dependent Recycling of the Calcium Channel Subunit α(2)δ-2
The α(2)δ subunits of voltage-gated calcium channels are important modulatory subunits that enhance calcium currents and may also have other roles in synaptogenesis. The antiepileptic and antiallodynic drug gabapentin (GBP) binds to the α(2)δ-1 and α(2)δ-2 isoforms of this protein, and its binding m...
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| Publicado no: | J Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6633565/ https://ncbi.nlm.nih.gov/pubmed/20861389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2700-10.2010 |
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