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LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α(2)δ-1 subunit

Voltage-gated Ca(2+) (Ca(V)) channels consist of a pore-forming α1 subunit, which determines the main functional and pharmacological attributes of the channel. The Ca(V)1 and Ca(V)2 channels are associated with auxiliary β- and α(2)δ-subunits. The molecular mechanisms involved in α(2)δ subunit traff...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kadurin, Ivan, Rothwell, Simon W., Lana, Beatrice, Nieto-Rostro, Manuela, Dolphin, Annette C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335561/
https://ncbi.nlm.nih.gov/pubmed/28256585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43802
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