The Ca(V)β Subunit Protects the I-II Loop of the Voltage-gated Calcium Channel Ca(V)2.2 from Proteasomal Degradation but Not Oligoubiquitination

Por Page, Karen M., Rothwell, Simon W., Dolphin, Annette C.
Publicado no J Biol Chem (2016)

Direct Gating of ATP-activated Ion Channels (P2X2 Receptors) by Lipophilic Attachment at the Outer End of the Second Transmembrane Domain

Por Rothwell, Simon W., Stansfeld, Phillip J., Bragg, Laricia, Verkhratsky, Alexej, North, R. Alan
Publicado em 2014

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α(2)δ-1 subunit

Por Kadurin, Ivan, Rothwell, Simon W., Lana, Beatrice, Nieto-Rostro, Manuela, Dolphin, Annette C.
Publicado no Sci Rep (2017)

P2X(7)R activation drives distinct IL-1 responses in dendritic cells compared to macrophages

Por Englezou, Pavlos C., Rothwell, Simon W., Ainscough, Joseph S., Brough, David, Landsiedel, Robert, Verkhratsky, Alexei, Kimber, Ian, Dearman, Rebecca J.
Publicado no Cytokine (2015)

Proteolytic maturation of α(2)δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels

Por Kadurin, Ivan, Ferron, Laurent, Rothwell, Simon W, Meyer, James O, Douglas, Leon R, Bauer, Claudia S, Lana, Beatrice, Margas, Wojciech, Alexopoulos, Orpheas, Nieto-Rostro, Manuela, Pratt, Wendy S, Dolphin, Annette C
Publicado no eLife (2016)

Disruption of the Key Ca(2+) Binding Site in the Selectivity Filter of Neuronal Voltage-Gated Calcium Channels Inhibits Channel Trafficking

Por Meyer, James O., Dahimene, Shehrazade, Page, Karen M., Ferron, Laurent, Kadurin, Ivan, Ellaway, Joseph I.J., Zhao, Pengxiang, Patel, Tarun, Rothwell, Simon W., Lin, Peipeng, Pratt, Wendy S., Dolphin, Annette C.
Publicado no Cell Rep (2019)