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Differential upregulation in DRG neurons of an α(2)δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury
The α(2)δ-1 protein is an auxiliary subunit of voltage-gated calcium channels, critical for neurotransmitter release. It is upregulated in dorsal root ganglion (DRG) neurons following sensory nerve injury, and is also the therapeutic target of the gabapentinoid drugs, which are efficacious in both e...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Lippincott Williams & Wilkins
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988960/ https://ncbi.nlm.nih.gov/pubmed/24315988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.12.001 |
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