Dominant-Negative Calcium Channel Suppression by Truncated Constructs Involves a Kinase Implicated in the Unfolded Protein Response

Expression of the calcium channel Ca(V)2.2 is markedly suppressed by coexpression with truncated constructs of Ca(V)2.2. Furthermore, a two-domain construct of Ca(V)2.1 mimicking an episodic ataxia-2 mutation strongly inhibited Ca(V)2.1 currents. We have now determined the specificity of this effect...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Page, Karen M., Heblich, Fay, Davies, Anthony, Butcher, Adrian J., Leroy, Jerôme, Bertaso, Federica, Pratt, Wendy S., Dolphin, Annette C.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2004
Sujets:
Cellular/Molecular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729303/
https://ncbi.nlm.nih.gov/pubmed/15190113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0553-04.2004
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