The importance of occupancy rather than affinity of Ca(V)β subunits for the calcium channel I–II linker in relation to calcium channel function

The Ca(V)β subunits of voltage-gated calcium channels regulate the trafficking and biophysical properties of these channels. We have taken advantage of mutations in the tyrosine residue within the alpha interaction domain (AID) in the I–II linker of Ca(V)2.2 which reduce, but do not abolish, the bin...

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Main Authors: Butcher, Adrian J, Leroy, Jérôme, Richards, Mark W, Pratt, Wendy S, Dolphin, Annette C
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2006
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817768/
https://ncbi.nlm.nih.gov/pubmed/16627564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.109744
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