Structural Basis of Poly(ADP-ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-associated and RING Domains (CHFR)

Cellular stress in early mitosis activates the antephase checkpoint, resulting in the decondensation of chromosomes and delayed mitotic progression. Checkpoint with forkhead-associated and RING domains (CHFR) is central to this checkpoint, and its activity is ablated in many tumors and cancer cell l...

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Detalles Bibliográficos
Main Authors: Oberoi, Jasmeen, Richards, Mark W., Crumpler, Simon, Brown, Nathan, Blagg, Julian, Bayliss, Richard
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998101/
https://ncbi.nlm.nih.gov/pubmed/20880844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.159855
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