Loading...
The Anti-Proliferative Effects of the CHFR Depend on the Forkhead Associated Domain, but not E3 Ligase Activity Mediated by Ring Finger Domain
The CHFR protein comprises fork head associated- (FHA) and RING-finger (RF) domain and is frequently downregulated in human colon and gastric cancers up to 50%. The loss of CHFR mRNA expression is a consequence of promoter methylation, suggesting a tumor suppressor role for this gene in gastrointest...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2008
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258000/ https://ncbi.nlm.nih.gov/pubmed/18335050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001776 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|