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A closed conformation of the Caenorhabditis elegans separase–securin complex

The protease separase plays a key role in sister chromatid disjunction and centriole disengagement. To maintain genomic stability, separase activity is strictly regulated by binding of an inhibitory protein, securin. Despite its central role in cell division, the separase and securin complex is poor...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Bachmann, Gudrun, Richards, Mark W., Winter, Anja, Beuron, Fabienne, Morris, Edward, Bayliss, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852461/
https://ncbi.nlm.nih.gov/pubmed/27249343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160032
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