Detection of the prodrug-activating enzyme carboxypeptidase G2 activity with chemical exchange saturation transfer magnetic resonance

Por Jamin, Yann, Eykyn, Thomas R., Poon, Evon, Springer, Caroline J., Robinson, Simon P.
Publicado no Mol Imaging Biol (2014)

Small-Molecule Activation of p53 Blocks Hypoxia-Inducible Factor 1α and Vascular Endothelial Growth Factor Expression In Vivo and Leads to Tumor Cell Apoptosis in Normoxia and Hypo...

Por Yang, Jun, Ahmed, Afshan, Poon, Evon, Perusinghe, Nina, de Haven Brandon, Alexis, Box, Gary, Valenti, Melanie, Eccles, Suzanne, Rouschop, Kasper, Wouters, Brad, Ashcroft, Margaret
Publicado em 2009

Small Molecule Inhibitors of Aurora-A Induce Proteasomal Degradation of N-Myc in Childhood Neuroblastoma

Por Brockmann, Markus, Poon, Evon, Berry, Teeara, Carstensen, Anne, Deubzer, Hedwig E., Rycak, Lukas, Jamin, Yann, Thway, Khin, Robinson, Simon P., Roels, Frederik, Witt, Olaf, Fischer, Matthias, Chesler, Louis, Eilers, Martin
Publicado no Cancer Cell (2013)

Evaluation of Clinically Translatable Magnetic Resonance Imaging Biomarkers of Therapeutic Response in the TH-MYCN Transgenic Mouse Model of Neuroblastoma

Por Jamin, Yann, Tucker, Elizabeth R., Poon, Evon S., Popov, Sergey, Vaughan, Lynsey, Boult, Jessica K.R., Webber, Hannah, Hallsworth, Albert, Baker, Lauren C.J., Jones, Chris, Koh, Dow-Mu, Pearson, Andrew D.J., Chesler, Louis, Robinson, Simon P.
Publicado no Radiology (2012)

Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression

Por Yang, Jun, Staples, Oliver, Thomas, Luke W., Briston, Thomas, Robson, Mathew, Poon, Evon, Simões, Maria L., El-Emir, Ethaar, Buffa, Francesca M., Ahmed, Afshan, Annear, Nicholas P., Shukla, Deepa, Pedley, Barbara R., Maxwell, Patrick H., Harris, Adrian L., Ashcroft, Margaret
Publicado em 2012

Cyclin-dependent kinase inhibitor AT7519 as a potential drug for MYCN-dependent neuroblastoma

Por Dolman, M. Emmy M., Poon, Evon, Ebus, Marli E., den Hartog, Ilona J.M., van Noesel, Carel J.M., Jamin, Yann, Hallsworth, Albert, Robinson, Simon P., Petrie, Kevin, Sparidans, Rolf W., Kok, Robbert J., Versteeg, Rogier, Caron, Huib N., Chesler, Louis, Molenaar, Jan J.
Publicado no Clin Cancer Res (2015)

The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma

Por Berry, Teeara, Luther, William, Bhatnagar, Namrata, Jamin, Yann, Poon, Evon, Sanda, Takaomi, Pei, Desheng, Sharma, Bandana, Vetharoy, Winston R., Hallsworth, Albert, Ahmad, Zai, Barker, Karen, Moreau, Lisa, Webber, Hannah, Wang, Wenchao, Liu, Qingsong, Perez-Atayde, Antonio, Rodig, Scott, Cheung, Nai-Kong, Raynaud, Florence, Hallberg, Bengt, Robinson, Simon P., Gray, Nathanael S., Pearson, Andrew D.J., Eccles, Suzanne A., Chesler, Louis, George, Rani E.
Publicado em 2012

Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease

Por Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet C., Petrie, Kevin, Schwalbe, Ed C., Barker, Karen, Boult, Jessica K.R., Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L., Poon, Evon, Robinson, Simon P., Ruddle, Ruth, Raynaud, Florence I., Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W., Wharton, Stephen B., Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S., Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Weiss, William A., Chesler, Louis, Clifford, Steven C.
Publicado no Cancer Cell (2015)