Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores

Por Tighe, Anthony, Staples, Oliver, Taylor, Stephen
Publicado em 2008

GSK-3 inhibitors induce chromosome instability

Por Tighe, Anthony, Ray-Sinha, Arpita, Staples, Oliver D, Taylor, Stephen S
Publicado em 2007

Characterization, chemical optimization and anti-tumour activity of a tubulin poison identified by a p53-based phenotypic screen

Por Staples, Oliver D., Hollick, Jonathan J., Campbell, Johanna, Higgins, Maureen, McCarthy, Anna R., Appleyard, Virginia, Murray, Karen E., Baker, Lee, Thompson, Alastair, Ronseaux, Sebastien, Slawin, Alexandra M.Z., Lane, David P., Westwood, Nicholas J., Lain, Sonia
Publicado em 2008

Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression

Por Yang, Jun, Staples, Oliver, Thomas, Luke W., Briston, Thomas, Robson, Mathew, Poon, Evon, Simões, Maria L., El-Emir, Ethaar, Buffa, Francesca M., Ahmed, Afshan, Annear, Nicholas P., Shukla, Deepa, Pedley, Barbara R., Maxwell, Patrick H., Harris, Adrian L., Ashcroft, Margaret
Publicado em 2012

Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

Por Lain, Sonia, Hollick, Jonathan J., Campbell, Johanna, Staples, Oliver D., Higgins, Maureen, Aoubala, Mustapha, McCarthy, Anna, Appleyard, Virginia, Murray, Karen E., Baker, Lee, Thompson, Alastair, Mathers, Joanne, Holland, Stephen J., Stark, Michael J.R., Pass, Georgia, Woods, Julie, Lane, David P., Westwood, Nicholas J.
Publicado em 2008