Prodrug-activating systems in suicide gene therapy

por Springer, Caroline J., Niculescu-Duvaz, Ion
Publicado 2000

Detection of the prodrug-activating enzyme carboxypeptidase G2 activity with chemical exchange saturation transfer magnetic resonance

por Jamin, Yann, Eykyn, Thomas R., Poon, Evon, Springer, Caroline J., Robinson, Simon P.
Publicado en Mol Imaging Biol (2014)

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

por Heidorn, Sonja J., Milagre, Carla, Whittaker, Steven, Nourry, Arnaud, Niculescu-Duvas, Ion, Dhomen, Nathalie, Hussain, Jahan, Reis-Filho, Jorge S., Springer, Caroline J., Pritchard, Catrin, Marais, Richard
Publicado 2010

A Novel, Selective and Efficacious Nanomolar Pyridopyrazinone Inhibitor of (V600E)BRAF

por Whittaker, Steven, Ménard, Delphine, Kirk, Ruth, Ogilvie, Lesley, Hedley, Douglas, Zambon, Alfonso, Lopes, Filipa, Preece, Natasha, Manne, Helen, Rana, Sareena, Lambros, Maryou, Reis-Filho, Jorge S, Marais, Richard, Springer, Caroline J
Publicado 2010

Contrasting effects of sunitinib within in vivo models of metastasis

por Welti, Jonathan C., Powles, Thomas, Foo, Shane, Gourlaouen, Morgane, Preece, Natasha, Foster, Julie, Frentzas, Sophia, Bird, Demelza, Sharpe, Kevin, van Weverwijk, Antoinette, Robertson, David, Soffe, Julie, Erler, Janine T., Pili, Roberto, Springer, Caroline J., Mather, Stephen J., Reynolds, Andrew R.
Publicado 2012

Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes

por Pedersen, Malin, Küsters-Vandevelde, Heidi V.N., Viros, Amaya, Groenen, Patricia J.T.A., Sanchez-Laorden, Berta, Gilhuis, Jacobus H., van Engen- van Grunsven, Ilse A., Renier, Willy, Schieving, Jolanda, Niculescu-Duvaz, Ion, Springer, Caroline J., Küsters, Benno, Wesseling, Pieter, Blokx, Willeke A.M., Marais, Richard
Publicado 2013

Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds

por Niculescu-Duvaz, Dan, Niculescu-Duvaz, Ion, Suijkerbuijk, Bart M.J.M., Ménard, Delphine, Zambon, Alfonso, Nourry, Arnaud, Davies, Lawrence, Manne, Helen A., Friedlos, Frank, Ogilvie, Lesley, Hedley, Douglas, Takle, Andrew K., Wilson, David M., Pons, Jean-Francois, Coulter, Tom, Kirk, Ruth, Cantarino, Neus, Whittaker, Steven, Marais, Richard, Springer, Caroline J.
Publicado 2010

RAS Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors

por Su, Fei, Viros, Amaya, Milagre, Carla, Trunzer, Kerstin, Bollag, Gideon, Spleiss, Olivia, Reis-Filho, Jorge S., Kong, Xiangju, Koya, Richard C., Flaherty, Keith T., Chapman, Paul B., Kim, Min Jung, Hayward, Robert, Martin, Matthew, Yang, Hong, Wang, Qiongqing, Hilton, Holly, Hang, Julie S., Noe, Johannes, Lambros, Maryou, Geyer, Felipe, Dhomen, Nathalie, Niculescu-Duvaz, Ion, Zambon, Alfonso, Niculescu-Duvaz, Dan, Preece, Natasha, Robert, Lídia, Otte, Nicholas J., Mok, Stephen, Kee, Damien, Ma, Yan, Zhang, Chao, Habets, Gaston, Burton, Elizabeth A., Wong, Bernice, Nguyen, Hoa, Kockx, Mark, Andries, Luc, Lestini, Brian, Nolop, Keith B., Lee, Richard J., Joe, Andrew K., Troy, James L., Gonzalez, Rene, Hutson, Thomas E., Puzanov, Igor, Chmielowski, Bartosz, Springer, Caroline J., McArthur, Grant A., Sosman, Jeffrey A., Lo, Roger S., Ribas, Antoni, Marais, Richard
Publicado 2012