Novel combination therapies for BRAF-mutant melanoma

Por McArthur, Grant A
Publicado no J Transl Med (2015)

Combination Therapies to Inhibit the RAF/MEK/ERK Pathway in Melanoma: We are not Done Yet

Por McArthur, Grant A.
Publicado no Front Oncol (2015)

The current state of targeted therapy in melanoma: this time it’s personal

Por Smalley, Keiran S M, McArthur, Grant A.
Publicado em 2012

Molecular Therapeutic Advances in Personalized Therapy of Melanoma and Non-Small Cell Lung Cancer

Por Kelleher, Fergal C., Solomon, Benjamin, McArthur, Grant A.
Publicado no J Pers Med (2012)

Targeted Deletion of the S-Phase-Specific Myc Antagonist Mad3 Sensitizes Neuronal and Lymphoid Cells to Radiation-Induced Apoptosis

Por Quéva, Christophe, McArthur, Grant A., Iritani, Brian M., Eisenman, Robert N.
Publicado em 2001

BRAF-targeted therapy and immune responses to melanoma

Por Ngiow, Shin Foong, Knight, Deborah A, Ribas, Antoni, McArthur, Grant A, Smyth, Mark J.
Publicado em 2013

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours

Por Wong, Stephen Q., Li, Jason, Salemi, Renato, Sheppard, Karen E., Hongdo Do, Tothill, Richard W., McArthur, Grant A., Dobrovic, Alexander
Publicado em 2013

MAD1 and p27(KIP1) Cooperate To Promote Terminal Differentiation of Granulocytes and To Inhibit Myc Expression and Cyclin E-CDK2 Activity

Por McArthur, Grant A., Foley, Kevin P., Fero, Matthew L., Walkley, Carl R., Deans, Andrew J., Roberts, James M., Eisenman, Robert N.
Publicado em 2002

Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer

Por Loi, Sherene, Sotiriou, Christos, Haibe-Kains, Benjamin, Lallemand, Francoise, Conus, Nelly M, Piccart, Martine J, Speed, Terence P, McArthur, Grant A
Publicado em 2009

c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiation

Por Poortinga, Gretchen, Wall, Meaghan, Sanij, Elaine, Siwicki, Kasia, Ellul, Jason, Brown, Daniel, Holloway, Timothy P., Hannan, Ross D., McArthur, Grant A.
Publicado em 2011

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies

Por Colebatch, Andrew J., Di Stefano, Leon, Wong, Stephen Q., Hannan, Ross D., Waring, Paul M., Dobrovic, Alexander, McArthur, Grant A., Papenfuss, Anthony T.
Publicado no Oncotarget (2016)

A First-Time-In-Human Phase I Clinical Trial of Bispecific Antibody-Targeted, Paclitaxel-Packaged Bacterial Minicells

Por Solomon, Benjamin J., Desai, Jayesh, Rosenthal, Mark, McArthur, Grant A., Pattison, Scott T., Pattison, Stacey L., MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Scott, Andrew M.
Publicado no PLoS One (2015)

Prognostic significance of plasma osteopontin in patients with loco-regionally advanced head and neck squamous cell carcinoma treated on TROG 02.02 Phase III trial

Por Lim, Annette, Rischin, Danny, Fisher, Richard, Cao, Hongbin, Kwok, Kathleen, Truong, Daniel, McArthur, Grant A., Young, Richard J., Giaccia, Amato, Peters, Lester, Le, Quynh-Thu
Publicado em 2011

mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription...

Por Hannan, Katherine M., Brandenburger, Yves, Jenkins, Anna, Sharkey, Kerith, Cavanaugh, Alice, Rothblum, Lawrence, Moss, Tom, Poortinga, Gretchen, McArthur, Grant A., Pearson, Richard B., Hannan, Ross D.
Publicado em 2003

A Microenvironment-Induced Myeloproliferative Syndrome Caused by RARγ Deficiency

Por Walkley, Carl R., Olsen, Gemma Haines, Dworkin, Sebastian, Fabb, Stewart A., Swann, Jeremy, McArthur, Grant A., Westmoreland, Susan V, Chambon, Pierre, Scadden, David T, Purton, Louise E.
Publicado em 2007

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma

Por Wong, Stephen Q., Behren, Andreas, Mar, Victoria J., Woods, Katherine, Li, Jason, Martin, Claire, Sheppard, Karen E., Wolfe, Rory, Kelly, John, Cebon, Jonathan, Dobrovic, Alexander, McArthur, Grant A.
Publicado no Oncotarget (2014)

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

Por Poortinga, Gretchen, Hannan, Katherine M, Snelling, Hayley, Walkley, Carl R, Jenkins, Anna, Sharkey, Kerith, Wall, Meaghan, Brandenburger, Yves, Palatsides, Manuela, Pearson, Richard B, McArthur, Grant A, Hannan, Ross D
Publicado em 2004

IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma

Por Frederiksen, Klaus Stensgaard, Lundsgaard, Dorthe, Freeman, Jeremy A., Hughes, Steven D., Holm, Thomas L., Skrumsager, Birte K., Petri, Andreas, Hansen, Lasse T., McArthur, Grant A., Davis, Ian D., Skak, Kresten
Publicado em 2008

Prognostic Significance of p16(INK4A) and Human Papillomavirus in Patients With Oropharyngeal Cancer Treated on TROG 02.02 Phase III Trial

Por Rischin, Danny, Young, Richard J., Fisher, Richard, Fox, Stephen B., Le, Quynh-Thu, Peters, Lester J., Solomon, Ben, Choi, Jimin, O'Sullivan, Brian, Kenny, Lizbeth M., McArthur, Grant A.
Publicado em 2010

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

Por Flaherty, Keith T., Puzanov, Igor, Kim, Kevin B., Ribas, Antoni, McArthur, Grant A., Sosman, Jeffrey A., O'Dwyer, Peter J., Lee, Richard J., Grippo, Joseph F., Nolop, Keith, Chapman, Paul B.
Publicado em 2010