Unexpected role of CDK4 in a G2/M checkpoint

Por Sheppard, Karen E, Pearson, Richard B, Hannan, Ross D
Publicado no Cell Cycle (2015)

AKT-independent PI3-K signaling in cancer – emerging role for SGK3

Por Bruhn, Maressa A, Pearson, Richard B, Hannan, Ross D, Sheppard, Karen E
Publicado em 2013

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours

Por Wong, Stephen Q., Li, Jason, Salemi, Renato, Sheppard, Karen E., Hongdo Do, Tothill, Richard W., McArthur, Grant A., Dobrovic, Alexander
Publicado em 2013

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma

Por Wong, Stephen Q., Behren, Andreas, Mar, Victoria J., Woods, Katherine, Li, Jason, Martin, Claire, Sheppard, Karen E., Wolfe, Rory, Kelly, John, Cebon, Jonathan, Dobrovic, Alexander, McArthur, Grant A.
Publicado no Oncotarget (2014)

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome

Por Tan, Lih Yin, Mintoff, Chris, Johan, M. Zahied, Ebert, Brenton W., Fedele, Clare, Zhang, You Fang, Szeto, Pacman, Sheppard, Karen E., McArthur, Grant A., Foster-Smith, Erwin, Ruszkiewicz, Andrew, Brown, Michael P., Bonder, Claudine S., Shackleton, Mark, Ebert, Lisa M.
Publicado no Oncotarget (2016)

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

Por Quin, Jaclyn, Chan, Keefe T., Devlin, Jennifer R., Cameron, Donald P., Diesch, Jeannine, Cullinane, Carleen, Ahern, Jessica, Khot, Amit, Hein, Nadine, George, Amee J., Hannan, Katherine M, Poortinga, Gretchen, Sheppard, Karen E., Khanna, Kum Kum, Johnstone, Ricky W., Drygin, Denis, McArthur, Grant A., Pearson, Richard B., Sanij, Elaine, Hannan, Ross D.
Publicado no Oncotarget (2016)

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

Por Kinross, Kathryn M., Montgomery, Karen G., Kleinschmidt, Margarete, Waring, Paul, Ivetac, Ivan, Tikoo, Anjali, Saad, Mirette, Hare, Lauren, Roh, Vincent, Mantamadiotis, Theo, Sheppard, Karen E., Ryland, Georgina L., Campbell, Ian G., Gorringe, Kylie L., Christensen, James G., Cullinane, Carleen, Hicks, Rodney J., Pearson, Richard B., Johnstone, Ricky W., McArthur, Grant A., Phillips, Wayne A.
Publicado em 2012

Response of BRAF mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis

Por Parmenter, Tiffany J., Kleinschmidt, Margarete, Kinross, Kathryn M., Bond, Simon T., Li, Jason, Kaadige, Mohan R., Rao, Aparna, Sheppard, Karen E., Hugo, Willy, Pupo, Gulietta M., Pearson, Richard B., McGee, Sean L., Long, Georgina V., Scolyer, Richard A., Rizos, Helen, Lo, Roger S., Cullinane, Carleen, Ayer, Donald E., Ribas, Antoni, Johnstone, Ricky W., Hicks, Rodney J., McArthur, Grant A.
Publicado em 2014

Deregulation of MYCN, LIN28B and LET7 in a Molecular Subtype of Aggressive High-Grade Serous Ovarian Cancers

Por Helland, Åslaug, Anglesio, Michael S., George, Joshy, Cowin, Prue A., Johnstone, Cameron N., House, Colin M., Sheppard, Karen E., Etemadmoghadam, Dariush, Melnyk, Nataliya, Rustgi, Anil K., Phillips, Wayne A., Johnsen, Hilde, Holm, Ruth, Kristensen, Gunnar B., Birrer, Michael J., Pearson, Richard B., Børresen-Dale, Anne-Lise, Huntsman, David G., deFazio, Anna, Creighton, Chad J., Smyth, Gordon K., Bowtell, David D. L.
Publicado em 2011