Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer

BACKGROUND: Within estrogen receptor-positive breast cancer (ER+ BC), the expression levels of proliferation-related genes can define two clinically distinct molecular subtypes. When treated with adjuvant tamoxifen, those ER+ BCs that are lowly proliferative have a good prognosis (luminal-A subtype)...

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Detalhes bibliográficos
Main Authors: Loi, Sherene, Sotiriou, Christos, Haibe-Kains, Benjamin, Lallemand, Francoise, Conus, Nelly M, Piccart, Martine J, Speed, Terence P, McArthur, Grant A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706265/
https://ncbi.nlm.nih.gov/pubmed/19552798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-37
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