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A Microenvironment-Induced Myeloproliferative Syndrome Caused by RARγ Deficiency

Myeloproliferative syndromes (MPS) are largely considered to be intrinsic to hematopoietic cells. Here, we demonstrate that mice null for retinoic acid receptor gamma (RARγ), have an MPS that was induced solely by the RARγ deficient microenvironment. Eight week old RARγ(-/-) mice had significantly i...

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Bibliografiske detaljer
Main Authors: Walkley, Carl R., Olsen, Gemma Haines, Dworkin, Sebastian, Fabb, Stewart A., Swann, Jeremy, McArthur, Grant A., Westmoreland, Susan V, Chambon, Pierre, Scadden, David T, Purton, Louise E.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974882/
https://ncbi.nlm.nih.gov/pubmed/17574023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.05.014
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