A Microenvironment-Induced Myeloproliferative Syndrome Caused by RARγ Deficiency

Myeloproliferative syndromes (MPS) are largely considered to be intrinsic to hematopoietic cells. Here, we demonstrate that mice null for retinoic acid receptor gamma (RARγ), have an MPS that was induced solely by the RARγ deficient microenvironment. Eight week old RARγ(-/-) mice had significantly i...

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Detalhes bibliográficos
Main Authors: Walkley, Carl R., Olsen, Gemma Haines, Dworkin, Sebastian, Fabb, Stewart A., Swann, Jeremy, McArthur, Grant A., Westmoreland, Susan V, Chambon, Pierre, Scadden, David T, Purton, Louise E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974882/
https://ncbi.nlm.nih.gov/pubmed/17574023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.05.014
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