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pRb Extrinsically Regulates Hematopoietic Stem Cells via Myeloid Cell -Bone Marrow Microenvironment Interactions

Hematopoiesis is maintained by stem cells (HSCs) that undergo fate decisions while integrating intrinsic and extrinsic signals, the latter principally derived from the bone marrow (BM) microenvironment. Cell cycle regulation can modulate stem cell fate. Whether this represents an intrinsic or extrin...

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Detalhes bibliográficos
Main Authors: Walkley, Carl R., Shea, Jeremy M., Sims, Natalie A., Purton, Louise E., Orkin, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768301/
https://ncbi.nlm.nih.gov/pubmed/17574022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.03.055
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