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Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis

Regulation of the cell cycle is intimately linked to erythroid differentiation, yet how these processes are coupled is not well understood. To gain insight into this coordinate regulation, we examined the role that the retinoblastoma protein (Rb), a central regulator of the cell cycle, plays in eryt...

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Detalles Bibliográficos
Main Authors: Sankaran, Vijay G., Orkin,, Stuart H., Walkley, Carl R.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238668/
https://ncbi.nlm.nih.gov/pubmed/18258751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1627208
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