pRb Extrinsically Regulates Hematopoietic Stem Cells via Myeloid Cell -Bone Marrow Microenvironment Interactions

Hematopoiesis is maintained by stem cells (HSCs) that undergo fate decisions while integrating intrinsic and extrinsic signals, the latter principally derived from the bone marrow (BM) microenvironment. Cell cycle regulation can modulate stem cell fate. Whether this represents an intrinsic or extrin...

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Bibliografiske detaljer
Main Authors: Walkley, Carl R., Shea, Jeremy M., Sims, Natalie A., Purton, Louise E., Orkin, Stuart H.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768301/
https://ncbi.nlm.nih.gov/pubmed/17574022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.03.055
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