A Microenvironment-Induced Myeloproliferative Syndrome Caused by RARγ Deficiency

Myeloproliferative syndromes (MPS) are largely considered to be intrinsic to hematopoietic cells. Here, we demonstrate that mice null for retinoic acid receptor gamma (RARγ), have an MPS that was induced solely by the RARγ deficient microenvironment. Eight week old RARγ(-/-) mice had significantly i...

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Bibliographic Details
Main Authors:	Walkley, Carl R., Olsen, Gemma Haines, Dworkin, Sebastian, Fabb, Stewart A., Swann, Jeremy, McArthur, Grant A., Westmoreland, Susan V, Chambon, Pierre, Scadden, David T, Purton, Louise E.
Format:	Artigo
Language:	Inglês
Published:	2007
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1974882/ https://ncbi.nlm.nih.gov/pubmed/17574023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.05.014
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A Microenvironment-Induced Myeloproliferative Syndrome Caused by RARγ Deficiency

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