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Targeted Deletion of the S-Phase-Specific Myc Antagonist Mad3 Sensitizes Neuronal and Lymphoid Cells to Radiation-Induced Apoptosis

The Mad family comprises four basic-helix-loop-helix/leucine zipper proteins, Mad1, Mxi1, Mad3, and Mad4, which heterodimerize with Max and function as transcriptional repressors. The balance between Myc-Max and Mad-Max complexes has been postulated to influence cell proliferation and differentiatio...

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Hlavní autoři: Quéva, Christophe, McArthur, Grant A., Iritani, Brian M., Eisenman, Robert N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86662/
https://ncbi.nlm.nih.gov/pubmed/11154258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.703-712.2001
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