Targeted Deletion of the S-Phase-Specific Myc Antagonist Mad3 Sensitizes Neuronal and Lymphoid Cells to Radiation-Induced Apoptosis

The Mad family comprises four basic-helix-loop-helix/leucine zipper proteins, Mad1, Mxi1, Mad3, and Mad4, which heterodimerize with Max and function as transcriptional repressors. The balance between Myc-Max and Mad-Max complexes has been postulated to influence cell proliferation and differentiatio...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Quéva, Christophe, McArthur, Grant A., Iritani, Brian M., Eisenman, Robert N.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2001
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.703-712.2001
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