MAD1 and p27(KIP1) Cooperate To Promote Terminal Differentiation of Granulocytes and To Inhibit Myc Expression and Cyclin E-CDK2 Activity

To understand how cellular differentiation is coupled to withdrawal from the cell cycle, we have focused on two negative regulators of the cell cycle, the MYC antagonist MAD1 and the cyclin-dependent kinase inhibitor p27(KIP1). Generation of Mad1/p27(KIP1) double-null mice revealed a number of synth...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	McArthur, Grant A., Foley, Kevin P., Fero, Matthew L., Walkley, Carl R., Deans, Andrew J., Roberts, James M., Eisenman, Robert N.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2002
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11940659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.9.3014-3023.2002
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!