Cryo-EM structure of the CDK2-cyclin A-CDC25A complex
Abstract The cell division cycle 25 phosphatases CDC25A, B and C regulate cell cycle transitions by dephosphorylating residues in the conserved glycine-rich loop of CDKs to activate their activity. Here, we present the cryo-EM structure of CDK2-cyclin A in complex with CDC25A at 2.7 Å resolution, pr...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2024-08-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-024-51135-w |
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