In The Spotlight: So you can teach old fibroblasts new tricks

Por Virós, Amaya, Girotti, Maria Romina, Marais, Richard
Publicado no Cancer Discov (2016)

Metformin accelerates the growth of BRAF(V600E)-driven melanoma by upregulating VEGF-A

Por Martin, Matthew J., Hayward, Robert, Viros, Amaya, Marais, Richard
Publicado em 2012

Improving Melanoma Classification by Integrating Genetic and Morphologic Features

Por Viros, Amaya, Fridlyand, Jane, Bauer, Juergen, Lasithiotakis, Konstantin, Garbe, Claus, Pinkel, Daniel, Bastian, Boris C
Publicado em 2008

Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling

Por Hirata, Eishu, Girotti, Maria Romina, Viros, Amaya, Hooper, Steven, Spencer-Dene, Bradley, Matsuda, Michiyuki, Larkin, James, Marais, Richard, Sahai, Erik
Publicado no Cancer Cell (2015)

Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53

Por Viros, Amaya, Sanchez-Laorden, Berta, Pedersen, Malin, Furney, Simon J., Rae, Joel, Hogan, Kate, Ejiama, Sarah, Girotti, Maria Romina, Cook, Martin, Dhomen, Nathalie, Marais, Richard
Publicado em 2014

Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells

Por Baenke, Franziska, Chaneton, Barbara, Smith, Matthew, Van Den Broek, Niels, Hogan, Kate, Tang, Haoran, Viros, Amaya, Martin, Matthew, Galbraith, Laura, Girotti, Maria R., Dhomen, Nathalie, Gottlieb, Eyal, Marais, Richard
Publicado no Mol Oncol (2015)

Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface

Por Tang, HaoRan, Leung, Leo, Saturno, Grazia, Viros, Amaya, Smith, Duncan, Di Leva, Gianpiero, Morrison, Eamonn, Niculescu-Duvaz, Dan, Lopes, Filipa, Johnson, Louise, Dhomen, Nathalie, Springer, Caroline, Marais, Richard
Publicado no Nat Commun (2017)

β-Catenin induces immortalization of melanocytes by suppressing p16(INK4a) expression and cooperates with N-Ras in melanoma development

Por Delmas, Véronique, Beermann, Friedrich, Martinozzi, Silvia, Carreira, Suzanne, Ackermann, Julien, Kumasaka, Mayuko, Denat, Laurence, Goodall, Jane, Luciani, Flavie, Viros, Amaya, Demirkan, Nese, Bastian, Boris C., Goding, Colin R., Larue, Lionel
Publicado em 2007

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

Por Orgaz, Jose L., Pandya, Pahini, Dalmeida, Rimple, Karagiannis, Panagiotis, Sanchez-Laorden, Berta, Viros, Amaya, Albrengues, Jean, Nestle, Frank O., Ridley, Anne J., Gaggioli, Cedric, Marais, Richard, Karagiannis, Sophia N., Sanz-Moreno, Victoria
Publicado em 2014

Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma

Por Girotti, Maria R, Pedersen, Malin, Sanchez-Laorden, Berta, Viros, Amaya, Turajlic, Samra, Niculescu-Duvaz, Dan, Zambon, Alfonso, Sinclair, John, Hayes, Andrew, Gore, Martin, Lorigan, Paul, Springer, Caroline, Larkin, James, Jorgensen, Claus, Marais, Richard
Publicado no Cancer Discov (2012)

Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes

Por Pedersen, Malin, Küsters-Vandevelde, Heidi V.N., Viros, Amaya, Groenen, Patricia J.T.A., Sanchez-Laorden, Berta, Gilhuis, Jacobus H., van Engen- van Grunsven, Ilse A., Renier, Willy, Schieving, Jolanda, Niculescu-Duvaz, Ion, Springer, Caroline J., Küsters, Benno, Wesseling, Pieter, Blokx, Willeke A.M., Marais, Richard
Publicado em 2013

A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity

Por Conde-Perez, Alejandro, Gros, Gwendoline, Longvert, Christine, Pedersen, Malin, Petit, Valérie, Aktary, Zackie, Viros, Amaya, Gesbert, Franck, Delmas, Véronique, Rambow, Florian, Bastian, Boris C., Campbell, Andrew D., Colombo, Sophie, Puig, Isabel, Bellacosa, Alfonso, Sansom, Owen, Marais, Richard, Van Kempen, Leon C. L. T., Larue, Lionel
Publicado no Nat Commun (2015)

Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

Por Girotti, Maria Romina, Lopes, Filipa, Preece, Natasha, Niculescu-Duvaz, Dan, Zambon, Alfonso, Davies, Lawrence, Whittaker, Steven, Saturno, Grazia, Viros, Amaya, Pedersen, Malin, Suijkerbuijk, Bart M.J.M., Menard, Delphine, McLeary, Robert, Johnson, Louise, Fish, Laura, Ejiama, Sarah, Sanchez-Laorden, Berta, Hohloch, Juliane, Carragher, Neil, Macleod, Kenneth, Ashton, Garry, Marusiak, Anna A., Fusi, Alberto, Brognard, John, Frame, Margaret, Lorigan, Paul, Marais, Richard, Springer, Caroline
Publicado no Cancer Cell (2015)

RAS Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors

Por Su, Fei, Viros, Amaya, Milagre, Carla, Trunzer, Kerstin, Bollag, Gideon, Spleiss, Olivia, Reis-Filho, Jorge S., Kong, Xiangju, Koya, Richard C., Flaherty, Keith T., Chapman, Paul B., Kim, Min Jung, Hayward, Robert, Martin, Matthew, Yang, Hong, Wang, Qiongqing, Hilton, Holly, Hang, Julie S., Noe, Johannes, Lambros, Maryou, Geyer, Felipe, Dhomen, Nathalie, Niculescu-Duvaz, Ion, Zambon, Alfonso, Niculescu-Duvaz, Dan, Preece, Natasha, Robert, Lídia, Otte, Nicholas J., Mok, Stephen, Kee, Damien, Ma, Yan, Zhang, Chao, Habets, Gaston, Burton, Elizabeth A., Wong, Bernice, Nguyen, Hoa, Kockx, Mark, Andries, Luc, Lestini, Brian, Nolop, Keith B., Lee, Richard J., Joe, Andrew K., Troy, James L., Gonzalez, Rene, Hutson, Thomas E., Puzanov, Igor, Chmielowski, Bartosz, Springer, Caroline J., McArthur, Grant A., Sosman, Jeffrey A., Lo, Roger S., Ribas, Antoni, Marais, Richard
Publicado em 2012