Renal cell carcinoma: diagnosis and treatment, 1994–2003

Por Hutson, Thomas E.
Publicado em 2005

Targeted therapy for renal cell carcinoma: a new treatment paradigm

Por Hutson, Thomas E.
Publicado em 2007

Targeted Therapies for the Treatment of Metastatic Renal Cell Carcinoma: Clinical Evidence

Por Hutson, Thomas E.
Publicado em 2011

New advancements and developments in treatment of renal cell carcinoma: focus on pazopanib

Por Cowey, C Lance, Sonpavde, Guru, Hutson, Thomas E
Publicado em 2010

A phase 1b clinical trial of the multi-targeted tyrosine kinase inhibitor lenvatinib (E7080) in combination with everolimus for treatment of metastatic renal cell carcinoma (RCC)

Por Molina, Ana M., Hutson, Thomas E., Larkin, James, Gold, Anne M., Wood, Karen, Carter, Dave, Motzer, Robert, Michaelson, M. Dror
Publicado em 2013

Sequential Therapy in Metastatic Renal Cell Carcinoma

Por Hirsch, Bradford R., Burke, John M., Agrawal, Manish, Hauke, Ralph J., Hutson, Thomas E., Doshi, Gury, Fleming, Mark T., Vogelzang, Nicholas J.
Publicado no J Kidney Cancer VHL (2016)

Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy...

Por Motzer, Robert J., Hutson, Thomas E., Hudes, Gary R., Figlin, Robert A., Martini, Jean-Francois, English, Patricia A., Huang, Xin, Valota, Olga, Williams, J. Andrew
Publicado em 2014

Two Phase II Trials of the Novel Akt Inhibitor Perifosine in Patients with Advanced Renal Cell Carcinoma Following Progression on VEGF-Targeted Therapy

Por Cho, Daniel C., Hutson, Thomas E., Samlowski, Wolfram, Sportelli, Peter, Somer, Brad, Richards, Paul, Sosman, Jeffrey A., Puzanov, Igor, Michaelson, M. Dror, Flaherty, Keith T., Figlin, Robert A, Vogelzang, Nicholas J
Publicado em 2012

Efficacy and Safety of Everolimus in Elderly Patients With Metastatic Renal Cell Carcinoma: An Exploratory Analysis of the Outcomes of Elderly Patients in the RECORD-1 Trial

Por Porta, Camillo, Calvo, Emiliano, Climent, Miguel A., Vaishampayan, Ulka, Osanto, Susanne, Ravaud, Alain, Bracarda, Sergio, Hutson, Thomas E., Escudier, Bernard, Grünwald, Viktor, Kim, Dennis, Panneerselvam, Ashok, Anak, Oezlem, Motzer, Robert J.
Publicado em 2012

Circulating proteins as potential biomarkers of sunitinib and interferon-α efficacy in treatment-naïve patients with metastatic renal cell carcinoma

Por Harmon, Charles S., DePrimo, Samuel E., Figlin, Robert A., Hudes, Gary R., Hutson, Thomas E., Michaelson, M. Dror, Négrier, Sylvie, Kim, Sindy T., Huang, Xin, Williams, J. Andrew, Eisen, Tim, Motzer, Robert J.
Publicado em 2013

The role of aberrant VHL/HIF pathway elements in predicting clinical outcome to pazopanib therapy in patients with metastatic clear-cell renal cell carcinoma

Por Choueiri, Toni K., Fay, André P., Gagnon, Robert, Lin, Ying, Bahamon, Brittany, Brown, Victoria, Rosenberg, Jonathan E., Hutson, Thomas E., Baker-Neblett, Katherine L., Carpenter, Christopher, Liu, Yuan, Pandite, Lini, Signoretti, Sabina
Publicado no Clin Cancer Res (2013)

Outcomes in Patients With Metastatic Renal Cell Carcinoma Who Develop Everolimus-Related Hyperglycemia and Hypercholesterolemia: Combined Subgroup Analyses of the RECORD-1 and REAC...

Por Bono, Petri, Oudard, Stephane, Bodrogi, Istvan, Hutson, Thomas E., Escudier, Bernard, Machiels, Jean-Pascal, Thompson, John A., Figlin, Robert A., Ravaud, Alain, Basaran, Mert, Porta, Camillo, Bracarda, Sergio, Brechenmacher, Thomas, Lin, Chinjune, Voi, Maurizio, Grunwald, Viktor, Motzer, Robert J.
Publicado no Clin Genitourin Cancer (2016)

Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma

Por Motzer, Robert J., Hutson, Thomas E., Tomczak, Piotr, Michaelson, M. Dror, Bukowski, Ronald M., Oudard, Stéphane, Negrier, Sylvie, Szczylik, Cezary, Pili, Roberto, Bjarnason, Georg A., Garcia-del-Muro, Xavier, Sosman, Jeffrey A., Solska, Ewa, Wilding, George, Thompson, John A., Kim, Sindy T., Chen, Isan, Huang, Xin, Figlin, Robert A.
Publicado em 2009

Double-Blind, Randomized Trial of Docetaxel Plus Vandetanib Versus Docetaxel Plus Placebo in Platinum-Pretreated Metastatic Urothelial Cancer

Por Choueiri, Toni K., Ross, Robert W., Jacobus, Susanna, Vaishampayan, Ulka, Yu, Evan Y., Quinn, David I., Hahn, Noah M., Hutson, Thomas E., Sonpavde, Guru, Morrissey, Stephanie C., Buckle, Geoffrey C., Kim, William Y., Petrylak, Daniel P., Ryan, Christopher W., Eisenberger, Mario A., Mortazavi, Amir, Bubley, Glenn J., Taplin, Mary-Ellen, Rosenberg, Jonathan E., Kantoff, Philip W.
Publicado em 2012

Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

Por Sosman, Jeffrey A., Kim, Kevin B., Schuchter, Lynn, Gonzalez, Rene, Pavlick, Anna C., Weber, Jeffrey S., McArthur, Grant A., Hutson, Thomas E., Moschos, Stergios J., Flaherty, Keith T., Hersey, Peter, Kefford, Richard, Lawrence, Donald, Puzanov, Igor, Lewis, Karl D., Amaravadi, Ravi K., Chmielowski, Bartosz, Lawrence, H. Jeffrey, Shyr, Yu, Ye, Fei, Li, Jiang, Nolop, Keith B., Lee, Richard J., Joe, Andrew K., Ribas, Antoni
Publicado em 2012

Cabozantinib versus everolimus in advanced renal cell carcinoma

Por Choueiri, Toni K., Escudier, Bernard, Powles, Thomas, Mainwaring, Paul, Rini, Brian I., Donskov, Frede, Hammers, Hans, Hutson, Thomas E., Lee, Jae-Lyun, Peltola, Katriina, Roth, Bruce J., Bjarnason, Georg A., Géczi, Lajos, Keam, Bhumsuk, Moroto, Pablo, Heng, Daniel Y. C., Schmidinger, Manuela, Kantoff, Philip W., Borgman, Anne, Hessel, Colin, Scheffold, Christian, Schwab, Gisela M., Tannir, Nizar M., Motzer, Robert J.
Publicado no N Engl J Med (2015)

Abiraterone and Increased Survival in Metastatic Prostate Cancer

Por de Bono, Johann S., Logothetis, Christopher J., Molina, Arturo, Fizazi, Karim, North, Scott, Chu, Luis, Chi, Kim N., Jones, Robert J., Goodman, Oscar B., Saad, Fred, Staffurth, John N., Mainwaring, Paul, Harland, Stephen, Flaig, Thomas W., Hutson, Thomas E., Cheng, Tina, Patterson, Helen, Hainsworth, John D., Ryan, Charles J., Sternberg, Cora N., Ellard, Susan L., Fléhon, Aude, Saleh, Mansoor, Scholz, Mark, Efstathiou, Eleni, Zivi, Andrea, Bianchini, Diletta, Loriot, Yohann, Chieffo, Nicole, Kheoh, Thian, Haqq, Christopher M., Scher, Howard I.
Publicado em 2011

RAS Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors

Por Su, Fei, Viros, Amaya, Milagre, Carla, Trunzer, Kerstin, Bollag, Gideon, Spleiss, Olivia, Reis-Filho, Jorge S., Kong, Xiangju, Koya, Richard C., Flaherty, Keith T., Chapman, Paul B., Kim, Min Jung, Hayward, Robert, Martin, Matthew, Yang, Hong, Wang, Qiongqing, Hilton, Holly, Hang, Julie S., Noe, Johannes, Lambros, Maryou, Geyer, Felipe, Dhomen, Nathalie, Niculescu-Duvaz, Ion, Zambon, Alfonso, Niculescu-Duvaz, Dan, Preece, Natasha, Robert, Lídia, Otte, Nicholas J., Mok, Stephen, Kee, Damien, Ma, Yan, Zhang, Chao, Habets, Gaston, Burton, Elizabeth A., Wong, Bernice, Nguyen, Hoa, Kockx, Mark, Andries, Luc, Lestini, Brian, Nolop, Keith B., Lee, Richard J., Joe, Andrew K., Troy, James L., Gonzalez, Rene, Hutson, Thomas E., Puzanov, Igor, Chmielowski, Bartosz, Springer, Caroline J., McArthur, Grant A., Sosman, Jeffrey A., Lo, Roger S., Ribas, Antoni, Marais, Richard
Publicado em 2012