Specific Investigation of Sample Handling Effects on Protease Activities and Absolute Serum Concentrations of Various Putative Peptidome Cancer Biomarkers

ανά van den Broek, Irene, Sparidans, Rolf W., Schellens, Jan H. M., Beijnen, Jos H.
Έκδοση 2010

Anti-GD2 Immunoliposomes for Targeted Delivery of the Survivin Inhibitor Sepantronium Bromide (YM155) to Neuroblastoma Tumor Cells

ανά Gholizadeh, Shima, Dolman, Emmy M., Wieriks, Rebecca, Sparidans, Rolf W., Hennink, Wim E., Kok, Robbert J.
Τόπος έκδοσης Pharm Res (2018)

OATP1A/1B, CYP3A, ABCB1, and ABCG2 limit oral availability of the NTRK inhibitor larotrectinib, while ABCB1 and ABCG2 also restrict its brain accumulation

ανά Wang, Yaogeng, Sparidans, Rolf W., Li, Wenlong, Lebre, Maria C., Beijnen, Jos H., Schinkel, Alfred H.
Τόπος έκδοσης Br J Pharmacol (2020)

P-Glycoprotein Limits Oral Availability, Brain Penetration, and Toxicity of an Anionic Drug, the Antibiotic Salinomycin

ανά Lagas, Jurjen S., Sparidans, Rolf W., van Waterschoot, Robert A. B., Wagenaar, Els, Beijnen, Jos H., Schinkel, Alfred H.
Έκδοση 2008

Quantification of cystine in human renal proximal tubule cells using liquid chromatography–tandem mass spectrometry

ανά Jamalpoor, Amer, Sparidans, Rolf W., Pou Casellas, Carla, Rood, Johannes J.M., Joshi, Mansi, Masereeuw, Rosalinde, Janssen, Manoe J.
Τόπος έκδοσης Biomed Chromatogr (2018)

Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies

ανά Deenen, Maarten J., Klümpen, Heinz-Josef, Richel, Dick J., Sparidans, Rolf W., Weterman, Mariette J., Beijnen, Jos H., Schellens, Jan H. M., Wilmink, Johanna W.
Έκδοση 2011

Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells

ανά Dolman, ME (Emmy) M, Harmsen, Stefan, Pieters, Ebel HE, Sparidans, Rolf W, Lacombe, Marie, Szokol, Bálint, Őrfi, László, Kéri, György, Storm, Gert, Hennink, Wim E, Kok, Robbert J
Έκδοση 2012

Extrahepatic metabolism of ibrutinib

ανά Rood, Johannes J. M., Jamalpoor, Amer, van Hoppe, Stephanie, van Haren, Matthijs J., Wasmann, Roeland E., Janssen, Manoe J., Schinkel, Alfred H., Masereeuw, Rosalinde, Beijnen, Jos H., Sparidans, Rolf W.
Τόπος έκδοσης Invest New Drugs (2020)

Midazolam metabolism in Cytochrome P450 3A knockout mice can be attributed to upregulated CYP2C enzymes

ανά van Waterschoot, Robert A.B., van Herwaarden, Antonius E., Lagas, Jurjen S., Sparidans, Rolf W., Wagenaar, Els, van der Kruijssen, Cornelia M.M., Goldstein, Joyce A., Zeldin, Darryl C., Beijnen, Jos H., Schinkel, Alfred H.
Έκδοση 2007

The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability

ανά Hahn, Cornelia S., Scott, David W., Xu, Xin, Roda, Mojtaba Abdul, Payne, Gregory A., Wells, J. Michael, Viera, Liliana, Winstead, Colleen J., Bratcher, Preston, Sparidans, Rolf W., Redegeld, Frank A., Jackson, Patricia L., Folkerts, Gert, Blalock, J. Edwin, Patel, Rakesh P., Gaggar, Amit
Τόπος έκδοσης Sci Adv (2015)

Cyclin-dependent kinase inhibitor AT7519 as a potential drug for MYCN-dependent neuroblastoma

ανά Dolman, M. Emmy M., Poon, Evon, Ebus, Marli E., den Hartog, Ilona J.M., van Noesel, Carel J.M., Jamin, Yann, Hallsworth, Albert, Robinson, Simon P., Petrie, Kevin, Sparidans, Rolf W., Kok, Robbert J., Versteeg, Rogier, Caron, Huib N., Chesler, Louis, Molenaar, Jan J.
Τόπος έκδοσης Clin Cancer Res (2015)

Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease

ανά Koelink, Pim J, Overbeek, Saskia A, Braber, Saskia, Morgan, Mary E, Henricks, Paul A J, Roda, Mojtaba Abdul, Verspaget, Hein W, Wolfkamp, Simone C, te Velde, Anje A, Jones, Caleb W, Jackson, Patricia L, Blalock, J Edwin, Sparidans, Rolf W, Kruijtzer, John A W, Garssen, Johan, Folkerts, Gert, Kraneveld, Aletta D
Έκδοση 2014