Pathophysiology and clinical implications of pulmonary arterial enlargement in COPD

Por Wells, J Michael, Dransfield, Mark T
Publicado em 2013

Bringing stability to the COPD patient: clinical and pharmacological considerations for frequent exacerbators

Por Gulati, Swati, Wells, J. Michael
Publicado no Drugs (2017)

MMP generated Matrikines

Por Wells, J. Michael, Gaggar, Amit, Blalock, J. Edwin
Publicado no Matrix Biol (2015)

Pulmonary Artery Enlargement Is Associated With Cardiac Injury During Severe Exacerbations of COPD

Por Wells, J. Michael, Morrison, Joshua B., Bhatt, Surya P., Nath, Hrudaya, Dransfield, Mark T.
Publicado no Chest (2016)

Determinants of successful completion of pulmonary rehabilitation in COPD

Por Brown, Angel T, Hitchcock, Jason, Schumann, Christopher, Wells, J Michael, Dransfield, Mark T, Bhatt, Surya P
Publicado no Int J Chron Obstruct Pulmon Dis (2016)

CT Scan-Measured Pulmonary Artery to Aorta Ratio and Echocardiography for Detecting Pulmonary Hypertension in Severe COPD

Por Iyer, Anand S., Wells, J. Michael, Vishin, Sonia, Bhatt, Surya P., Wille, Keith M., Dransfield, Mark T.
Publicado em 2014

Sputum PGP is reduced by azithromycin treatment in patients with COPD and correlates with exacerbations

Por O'Reilly, Philip J, Jackson, Patricia L, Wells, J Michael, Dransfield, Mark T, Scanlon, Paul D, Blalock, J Edwin
Publicado em 2013

Risk factors for COPD exacerbations in inhaled medication users: the COPDGene study biannual longitudinal follow-up prospective cohort

Por Busch, Robert, Han, MeiLan K., Bowler, Russell P., Dransfield, Mark T., Wells, J Michael, Regan, Elizabeth A., Hersh, Craig P.
Publicado no BMC Pulm Med (2016)

β-Blockers for the prevention of acute exacerbations of chronic obstructive pulmonary disease (βLOCK COPD): a randomised controlled study protocol

Por Bhatt, Surya P, Connett, John E, Voelker, Helen, Lindberg, Sarah M, Westfall, Elizabeth, Wells, J Michael, Lazarus, Stephen C, Criner, Gerard J, Dransfield, Mark T
Publicado no BMJ Open (2016)

A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease

Por Wells, J. Michael, Jackson, Patricia L., Viera, Liliana, Bhatt, Surya P., Gautney, Joshua, Handley, Guy, King, R. Wilson, Xu, Xin, Gaggar, Amit, Bailey, William C., Dransfield, Mark T., Blalock, J. Edwin
Publicado no Am J Respir Crit Care Med (2015)

Pulmonary Artery Enlargement is Associated with RV Dysfunction and Loss of Blood Volume in Small Pulmonary Vessels in Chronic Obstructive Pulmonary Disease

Por Wells, J. Michael, Iyer, Anand S., Rahaghi, Farbod N., Bhatt, Surya P., Gupta, Himanshu, Denney, Thomas S., Lloyd, Steven G., Dell’Italia, Louis J., Nath, Hrudaya, San Jose Estepar, Raul, Washko, George R., Dransfield, Mark T.
Publicado no Circ Cardiovasc Imaging (2015)

IREB2 and GALC Are Associated with Pulmonary Artery Enlargement in Chronic Obstructive Pulmonary Disease

Por Lee, Jin Hwa, Cho, Michael H., Hersh, Craig P., McDonald, Merry-Lynn N., Wells, J. Michael, Dransfield, Mark T., Bowler, Russell P., Lynch, David A., Lomas, David A., Crapo, James D., Silverman, Edwin K.
Publicado no Am J Respir Cell Mol Biol (2015)

Arterial and venous pulmonary vascular morphology and their relationship to findings in cardiac MRI in smokers

Por Rahaghi, Farbod. N., Wells, J. Michael, Come, Carolyn E., de La Bruere, I., Bhatt, Surya, Ross, James C., Vegas-Sánchez-Ferrero, Gonzalo, Diaz, Alejandro A., Minhas, Jasleen, Dransfield, Mark T., Estépar, Raul San José, Washko, George R.
Publicado no J Comput Assist Tomogr (2016)

An Aberrant Leukotriene A(4) Hydrolase–Proline-Glycine-Proline Pathway in the Pathogenesis of Chronic Obstructive Pulmonary Disease

Por Wells, J. Michael, O’Reilly, Philip J., Szul, Tomasz, Sullivan, Daniel I., Handley, Guy, Garrett, Chris, McNicholas, Carmel M., Roda, Mojtaba Abdul, Miller, Bruce E., Tal-Singer, Ruth, Gaggar, Amit, Rennard, Stephen I., Jackson, Patricia L., Blalock, J. Edwin
Publicado no Am J Respir Crit Care Med (2014)

The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability

Por Hahn, Cornelia S., Scott, David W., Xu, Xin, Roda, Mojtaba Abdul, Payne, Gregory A., Wells, J. Michael, Viera, Liliana, Winstead, Colleen J., Bratcher, Preston, Sparidans, Rolf W., Redegeld, Frank A., Jackson, Patricia L., Folkerts, Gert, Blalock, J. Edwin, Patel, Rakesh P., Gaggar, Amit
Publicado no Sci Adv (2015)

GDF-15 plasma levels in chronic obstructive pulmonary disease are associated with subclinical coronary artery disease

Por Martinez, Carlos H., Freeman, Christine M., Nelson, Joshua D., Murray, Susan, Wang, Xin, Budoff, Matthew J., Dransfield, Mark T., Hokanson, John E., Kazerooni, Ella A., Kinney, Gregory L., Regan, Elizabeth A., Wells, J. Michael, Martinez, Fernando J., Han, MeiLan K., Curtis, Jeffrey L.
Publicado no Respir Res (2017)

A ferret model of COPD-related chronic bronchitis

Por Raju, S. Vamsee, Kim, Hyunki, Byzek, Stephen A., Tang, Li Ping, Trombley, John E., Jackson, Patricia, Rasmussen, Lawrence, Wells, J. Michael, Libby, Emily Falk, Dohm, Erik, Winter, Lindy, Samuel, Sharon L., Zinn, Kurt R., Blalock, J. Edwin, Schoeb, Trenton R., Dransfield, Mark T., Rowe, Steven M.
Publicado no JCI Insight (2016)

Acute Exacerbations and Lung Function Loss in Smokers with and without Chronic Obstructive Pulmonary Disease

Por Dransfield, Mark T., Kunisaki, Ken M., Strand, Matthew J., Anzueto, Antonio, Bhatt, Surya P., Bowler, Russell P., Criner, Gerard J., Curtis, Jeffrey L., Hanania, Nicola A., Nath, Hrudaya, Putcha, Nirupama, Roark, Sarah E., Wan, Emily S., Washko, George R., Wells, J. Michael, Wendt, Christine H., Make, Barry J.
Publicado no Am J Respir Crit Care Med (2017)

Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism

Por Zhao, Xue-Ke, Che, Pulin, Cheng, Ming-Liang, Zhang, Quan, Mu, Mao, Li, Hong, Luo, Yuan, Liang, Yue-Dong, Luo, Xin-Hua, Gao, Chang-Qing, Jackson, Patricia L., Wells, J. Michael, Zhou, Yong, Hu, Meng, Cai, Guoqiang, Thannickal, Victor J., Steele, Chad, Blalock, J. Edwin, Han, Xiaosi, Chen, Ching-Yi, Ding, Qiang
Publicado no PLoS One (2016)

Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study

Por Wells, J. Michael, Estepar, Raul San Jose, McDonald, Merry-Lynn N., Bhatt, Surya P., Diaz, Alejandro A., Bailey, William C., Jacobson, Francine L., Dransfield, Mark T., Washko, George R., Make, Barry J., Casaburi, Richard, van Beek, Edwin J. R., Hoffman, Eric A., Sciurba, Frank C., Crapo, James D., Silverman, Edwin K., Hersh, Craig P.
Publicado no BMC Pulm Med (2016)