Sputum PGP is reduced by azithromycin treatment in patients with COPD and correlates with exacerbations

RATIONALE: Proline–glycine–proline (PGP), a neutrophil chemoattractant derived from the enzymatic breakdown of collagen, is elevated in sputum of patients with chronic obstructive pulmonary disease (COPD) and may contribute to disease progression. Whether sputum levels of PGP respond to therapy for...

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Detalhes bibliográficos
Main Authors: O'Reilly, Philip J, Jackson, Patricia L, Wells, J Michael, Dransfield, Mark T, Scanlon, Paul D, Blalock, J Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2013
Assuntos:
Respiratory Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884851/
https://ncbi.nlm.nih.gov/pubmed/24366582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2013-004140
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