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Quantification of cystine in human renal proximal tubule cells using liquid chromatography–tandem mass spectrometry

Nephropathic cystinosis is characterized by abnormal intralysosomal accumulation of cystine throughout the body, causing irreversible damage to various organs, particularly the kidneys. Cysteamine, the currently available treatment, can reduce lysosomal cystine and postpone disease progression. Howe...

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Detalhes bibliográficos
Publicado no:Biomed Chromatogr
Main Authors: Jamalpoor, Amer, Sparidans, Rolf W., Pou Casellas, Carla, Rood, Johannes J.M., Joshi, Mansi, Masereeuw, Rosalinde, Janssen, Manoe J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055858/
https://ncbi.nlm.nih.gov/pubmed/29517154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.4238
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