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Quantification of cystine in human renal proximal tubule cells using liquid chromatography–tandem mass spectrometry

Nephropathic cystinosis is characterized by abnormal intralysosomal accumulation of cystine throughout the body, causing irreversible damage to various organs, particularly the kidneys. Cysteamine, the currently available treatment, can reduce lysosomal cystine and postpone disease progression. Howe...

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Vydáno v:Biomed Chromatogr
Hlavní autoři: Jamalpoor, Amer, Sparidans, Rolf W., Pou Casellas, Carla, Rood, Johannes J.M., Joshi, Mansi, Masereeuw, Rosalinde, Janssen, Manoe J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055858/
https://ncbi.nlm.nih.gov/pubmed/29517154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.4238
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