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Quantification of cystine in human renal proximal tubule cells using liquid chromatography–tandem mass spectrometry

Nephropathic cystinosis is characterized by abnormal intralysosomal accumulation of cystine throughout the body, causing irreversible damage to various organs, particularly the kidneys. Cysteamine, the currently available treatment, can reduce lysosomal cystine and postpone disease progression. Howe...

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Detalles Bibliográficos
Publicado en:Biomed Chromatogr
Main Authors: Jamalpoor, Amer, Sparidans, Rolf W., Pou Casellas, Carla, Rood, Johannes J.M., Joshi, Mansi, Masereeuw, Rosalinde, Janssen, Manoe J.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055858/
https://ncbi.nlm.nih.gov/pubmed/29517154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.4238
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