ロード中...

P-Glycoprotein Limits Oral Availability, Brain Penetration, and Toxicity of an Anionic Drug, the Antibiotic Salinomycin

Salinomycin is a polyether organic anion that is extensively used as a coccidiostatic antibiotic in poultry and commonly fed to ruminant animals to improve feed efficiency. However, salinomycin also causes severe toxicity when accidentally fed to animals in high doses. In addition, humans are highly...

詳細記述

保存先:
書誌詳細
主要な著者: Lagas, Jurjen S., Sparidans, Rolf W., van Waterschoot, Robert A. B., Wagenaar, Els, Beijnen, Jos H., Schinkel, Alfred H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258498/
https://ncbi.nlm.nih.gov/pubmed/18195061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01041-07
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!