Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression

Hsp70 proteins represent a family of chaperones that regulate cellular homeostasis and are required for cancer cell survival. However, their function and regulation in mitosis remain unknown. In this paper, we show that the major inducible cytoplasmic Hsp70 isoform, Hsp72, is required for assembly o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: O’Regan, Laura, Sampson, Josephina, Richards, Mark W., Knebel, Axel, Roth, Daniel, Hood, Fiona E., Straube, Anne, Royle, Stephen J., Bayliss, Richard, Fry, Andrew M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2015
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427782/
https://ncbi.nlm.nih.gov/pubmed/25940345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409151
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