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Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression

Hsp70 proteins represent a family of chaperones that regulate cellular homeostasis and are required for cancer cell survival. However, their function and regulation in mitosis remain unknown. In this paper, we show that the major inducible cytoplasmic Hsp70 isoform, Hsp72, is required for assembly o...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: O’Regan, Laura, Sampson, Josephina, Richards, Mark W., Knebel, Axel, Roth, Daniel, Hood, Fiona E., Straube, Anne, Royle, Stephen J., Bayliss, Richard, Fry, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427782/
https://ncbi.nlm.nih.gov/pubmed/25940345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409151
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