Efficient consideration of coordinated water molecules improves computational protein-protein and protein-ligand docking discrimination

per Pavlovicz, Ryan E., Park, Hahnbeom, DiMaio, Frank
Publicat a PLoS Comput Biol (2020)

Conformational Changes in the Lower Palm Domain of ASIC1a Contribute to Desensitization and RFamide Modulation

per Frey, Erin N., Pavlovicz, Ryan E., Wegman, Clem John, Li, Chenglong, Askwith, Candice C.
Publicat 2013

Autocatalytic Cleavage of Human γ-Glutamyl Transpeptidase Is Highly Dependent on N-Glycosylation at Asparagine 95

per West, Matthew B., Wickham, Stephanie, Quinalty, Leslie M., Pavlovicz, Ryan E., Li, Chenglong, Hanigan, Marie H.
Publicat 2011

Identification of a Negative Allosteric Site on Human α4β2 and α3β4 Neuronal Nicotinic Acetylcholine Receptors

per Pavlovicz, Ryan E., Henderson, Brandon J., Bonnell, Andrew B., Boyd, R. Thomas, McKay, Dennis B., Li, Chenglong
Publicat 2011

Discovery of Novel α4β2 Neuronal Nicotinic Receptor Modulators through Structure-Based Virtual Screening

per Mahasenan, Kiran V., Pavlovicz, Ryan E., Henderson, Brandon J., González-Cestari, Tatiana F., Yi, Bitna, McKay, Dennis B., Li, Chenglong
Publicat 2011

Discovery of benzamide analogs as negative allosteric modulators of human neuronal nicotinic receptors: Pharmacophore modeling and structure-activity relationship studies

per Yi, Bitna, Long, Sihui, González-Cestari, Tatiana F., Henderson, Brandon J., Pavlovicz, Ryan E., Werbovetz, Karl, Li, Chenglong, McKay, Dennis B.
Publicat a Bioorg Med Chem (2013)

Synthesis of apo-13- and apo-15-lycopenoids, cleavage products of lycopene that are retinoic acid antagonists

per Narayanasamy, Sureshbabu, Sun, Jian, Pavlovicz, Ryan E., Eroglu, Abdulkerim, Rush, Cassandra E., Sunkel, Benjamin D., Li, Chenglong, Harrison, Earl H., Curley, Robert W.
Publicat a J Lipid Res (2017)

Defining the Putative Inhibitory Site for a Selective Negative Allosteric Modulator of Human α4β2 Neuronal Nicotinic Receptors

per Henderson, Brandon J., González-Cestari, Tatiana F., Yi, Bitna, Pavlovicz, Ryan E., Boyd, R. Thomas, Li, Chenglong, Bergmeier, Stephen C., McKay, Dennis B.
Publicat 2012

Structure-activity relationship studies of sulfonylpiperazine analogs as novel negative allosteric modulators of human neuronal nicotinic receptors

per Henderson, Brandon J., Carper, Daniel J., Gonzáez-Cestari, Tatiana F., Yi, Bitna, Mahasenan, Kiran, Pavlovicz, Ryan E., Dalefield, Martin L., Coleman, Robert S., Li, Chenglong, McKay, Dennis B.
Publicat 2011

The zinc transporter SLC39A8 is a negative feedback regulator of NF-κB through zinc-mediated inhibition of IKK

per Liu, Ming-Jie, Bao, Shengying, Gálvez-Peralta, Marina, Pyle, Charlie J., Rudawsky, Andrew C., Pavlovicz, Ryan E., Killilea, David W., Li, Chenglong, Nebert, Daniel W., Wewers, Mark D., Knoell, Daren L.
Publicat 2013

Alkaloids from Microcos paniculata with Cytotoxic and Nicotinic Receptor Antagonistic Activities

per Still, Patrick C., Yi, Bitna, González-Cestari, Tatiana F., Pan, Li, Pavlovicz, Ryan E., Chai, Hee-Byung, Ninh, Tran Ngoc, Li, Chenglong, Soejarto, Djaja Djendoel, McKay, Dennis B., Kinghorn, A. Douglas
Publicat 2013

Negative Allosteric Modulators That Target Human α4β2 Neuronal Nicotinic Receptors

per Henderson, Brandon J., Pavlovicz, Ryan E., Allen, Jerad D., González-Cestari, Tatiana F., Orac, Crina M., Bonnell, Andrew B., Zhu, Michael X., Boyd, R. Thomas, Li, Chenglong, Bergmeier, Stephen C., McKay, Dennis B.
Publicat 2010

Effect of Novel Negative Allosteric Modulators of Neuronal Nicotinic Receptors on Cells Expressing Native and Recombinant Nicotinic Receptors: Implications for Drug Discovery

per González-Cestari, Tatiana F., Henderson, Brandon J., Pavlovicz, Ryan E., McKay, Susan B., El-Hajj, Raed A., Pulipaka, Aravinda B., Orac, Crina M., Reed, Damon D., Boyd, R. Thomas, Zhu, Michael X., Li, Chenglong, Bergmeier, Stephen C., McKay, Dennis B.
Publicat 2009

CaMKII-Based Regulation of Voltage-Gated Na(+) Channel in Cardiac Disease

per Koval, Olha M., Snyder, Jedidiah S., Wolf, Roseanne M., Pavlovicz, Ryan E., Glynn, Patric, Curran, Jerry, Leymaster, Nicholas D., Dun, Wen, Wright, Patrick J., Cardona, Natalia, Qian, Lan, Mitchell, Colleen C., Boyden, Penelope A., Binkley, Philip F., Li, Chenglong, Anderson, Mark E., Mohler, Peter J., Hund, Thomas J.
Publicat 2012

Modulation of DNA Methylation by a Sesquiterpene Lactone Parthenolide

per Liu, Zhongfa, Liu, Shujun, Xie, Zhiliang, Pavlovicz, Ryan E., Wu, Jiejun, Chen, Ping, Aimiuwu, Josephine, Pang, Jiuxia, Bhasin, Deepak, Neviani, Paolo, Fuchs, James R., Plass, Christoph, Li, Pui-Kai, Li, Chenglong, Huang, Tim H.-M., Wu, Lai-Chu, Rush, Laura, Wang, Hongyan, Perrotti, Danilo, Marcucci, Guido, Chan, Kenneth K.
Publicat 2009

HDAC6 Deacetylates and Ubiquitinates MSH2 to Maintain Proper Levels of MutSα

per Zhang, Mu, Xiang, Shengyan, Joo, Heui-Yun, Wang, Lei, Williams, Kendra A., Liu, Wei, Hu, Chen, Tong, Dan, Haakenson, Joshua, Wang, Chuangui, Zhang, Shengping, Pavlovicz, Ryan E., Jones, Amanda, Schmidt, Kristina H., Tang, Jinfu, Dong, Huiqin, Shan, Bin, Fang, Bin, Radhakrishnan, Rangasudhagar, Glazer, Peter M., Matthias, Patrick, Koomen, John, Seto, Edward, Bepler, Gerold, Nicosia, Santo V., Chen, Jiandong, Li, Chenglong, Gu, Liya, Li, Guo-Min, Bai, Wenlong, Wang, Hengbin, Zhang, Xiaohong
Publicat 2014

Macromolecular modeling and design in Rosetta: recent methods and frameworks

per Koehler Leman, Julia, Weitzner, Brian D, Lewis, Steven M, Adolf-Bryfogle, Jared, Alam, Nawsad, Alford, Rebecca F, Aprahamian, Melanie, Baker, David, Barlow, Kyle A, Barth, Patrick, Basanta, Benjamin, Bender, Brian J, Blacklock, Kristin, Bonet, Jaume, Boyken, Scott, Bradley, Phil, Bystroff, Chris, Conway, Patrick, Cooper, Seth, Correia, Bruno E, Coventry, Brian, Das, Rhiju, De Jong, René M, DiMaio, Frank, Dsilva, Lorna, Dunbrack, Roland, Ford, Alex, Frenz, Brandon, Fu, Darwin Y, Geniesse, Caleb, Goldschmidt, Lukasz, Gowthaman, Ragul, Gray, Jeffrey J, Gront, Dominik, Guffy, Sharon, Horowitz, Scott, Huang, Po-Ssu, Huber, Thomas, Jacobs, Tim M, Jeliazkov, Jeliazko R, Johnson, David K, Kappel, Kalli, Karanicolas, John, Khakzad, Hamed, Khar, Karen R, Khare, Sagar D, Khatib, Firas, Khramushin, Alisa, King, Indigo C, Kleffner, Robert, Koepnick, Brian, Kortemme, Tanja, Kuenze, Georg, Kuhlman, Brian, Kuroda, Daisuke, Labonte, Jason W, Lai, Jason K, Lapidoth, Gideon, Leaver-Fay, Andrew, Lindert, Steffen, Linsky, Thomas, London, Nir, Lubin, Joseph H, Lyskov, Sergey, Maguire, Jack, Malmström, Lars, Marcos, Enrique, Marcu, Orly, Marze, Nicholas A, Meiler, Jens, Moretti, Rocco, Mulligan, Vikram Khipple, Nerli, Santrupti, Norn, Christoffer, Ó’Conchúir, Shane, Ollikainen, Noah, Ovchinnikov, Sergey, Pacella, Michael S, Pan, Xingjie, Park, Hahnbeom, Pavlovicz, Ryan E, Pethe, Manasi, Pierce, Brian G, Pilla, Kala Bharath, Raveh, Barak, Renfrew, P Douglas, Roy Burman, Shourya S, Rubenstein, Aliza, Sauer, Marion F, Scheck, Andreas, Schief, William, Schueler-Furman, Ora, Sedan, Yuval, Sevy, Alexander M, Sgourakis, Nikolaos G, Shi, Lei, Siegel, Justin, Silva, Daniel-Adriano, Smith, Shannon, Song, Yifan, Stein, Amelie, Szegedy, Maria, Teets, Frank D, Thyme, Summer B, Wang, Ray Yu-Ruei, Watkins, Andrew, Zimmerman, Lior, Bonneau, Richard
Publicat a Nat Methods (2020)