Negative Allosteric Modulators That Target Human α4β2 Neuronal Nicotinic Receptors

Allosteric modulation of neuronal nicotinic acetylcholine receptors (nAChRs) is considered to be one of the most promising approaches for therapeutics. We have previously reported on the pharmacological activity of several compounds that act as negative allosteric modulators (NAMs) of nAChRs. In the...

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Main Authors: Henderson, Brandon J., Pavlovicz, Ryan E., Allen, Jerad D., González-Cestari, Tatiana F., Orac, Crina M., Bonnell, Andrew B., Zhu, Michael X., Boyd, R. Thomas, Li, Chenglong, Bergmeier, Stephen C., McKay, Dennis B.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Neuropharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939664/
https://ncbi.nlm.nih.gov/pubmed/20551292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.168211
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