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Defining the Putative Inhibitory Site for a Selective Negative Allosteric Modulator of Human α4β2 Neuronal Nicotinic Receptors

[Image: see text] Neuronal nicotinic receptors (nAChRs) have been implicated in several diseases and disorders such as autism spectrum disorders, Alzheimer’s disease, Parkinson’s disease, epilepsy, and nicotine addiction. To understand the role of nAChRs in these conditions, it would be beneficial t...

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Detalhes bibliográficos
Main Authors: Henderson, Brandon J., González-Cestari, Tatiana F., Yi, Bitna, Pavlovicz, Ryan E., Boyd, R. Thomas, Li, Chenglong, Bergmeier, Stephen C., McKay, Dennis B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447398/
https://ncbi.nlm.nih.gov/pubmed/23019495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300035f
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