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Structure-activity relationship studies of sulfonylpiperazine analogs as novel negative allosteric modulators of human neuronal nicotinic receptors

Neuronal nicotinic receptors have been implicated in several diseases and disorders such as: autism, Alzheimer’s disease, Parkinson’s disease, epilepsy, and various forms of addiction. To understand the role of nicotinic receptors in these conditions, it would be beneficial to have selective molecul...

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Main Authors: Henderson, Brandon J., Carper, Daniel J., Gonzáez-Cestari, Tatiana F., Yi, Bitna, Mahasenan, Kiran, Pavlovicz, Ryan E., Dalefield, Martin L., Coleman, Robert S., Li, Chenglong, McKay, Dennis B.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240716/
https://ncbi.nlm.nih.gov/pubmed/22060139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201294r
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