CaMKII-Based Regulation of Voltage-Gated Na(+) Channel in Cardiac Disease

BACKGROUND: Human gene variants affecting ion channel biophysical activity and/or membrane localization are linked with potentially fatal cardiac arrhythmias. However, the mechanism for many human arrhythmia variants remains undefined despite over a decade of investigation. Post-translational modula...

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Hlavní autoři: Koval, Olha M., Snyder, Jedidiah S., Wolf, Roseanne M., Pavlovicz, Ryan E., Glynn, Patric, Curran, Jerry, Leymaster, Nicholas D., Dun, Wen, Wright, Patrick J., Cardona, Natalia, Qian, Lan, Mitchell, Colleen C., Boyden, Penelope A., Binkley, Philip F., Li, Chenglong, Anderson, Mark E., Mohler, Peter J., Hund, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811023/
https://ncbi.nlm.nih.gov/pubmed/23008441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.105320
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