CaMKII inhibition rescues pro-arrhythmic phenotypes in model of human ankyrin-B syndrome

BACKGROUND: Cardiovascular disease is a leading cause of death worldwide. Arrhythmias are associated with significant morbidity and mortality related to cardiovascular disease. Recent work illustrates that many cardiac arrhythmias are initiated by a pathologic imbalance between kinase and phosphatas...

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Main Authors: DeGrande, Sean, Nixon, Derek, Koval, Olha, Curran, Jerald W, Wright, Patrick, Wang, Qiongling, Kashef, Farshid, Chiang, David, Li, Na, Wehrens, Xander HT, Anderson, Mark E., Hund, Thomas J., Mohler, Peter J.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630478/
https://ncbi.nlm.nih.gov/pubmed/23059182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2012.08.026
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