The zinc transporter SLC39A8 is a negative feedback regulator of NF-κB through zinc-mediated inhibition of IKK

Activation of the transcription factor NF-κB is essential to innate immune function and requires strict regulation. The micronutrient zinc modulates proper host defense and zinc deficiency is associated with elevated inflammation and worse outcomes in response to bacterial infection and sepsis. Prev...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Liu, Ming-Jie, Bao, Shengying, Gálvez-Peralta, Marina, Pyle, Charlie J., Rudawsky, Andrew C., Pavlovicz, Ryan E., Killilea, David W., Li, Chenglong, Nebert, Daniel W., Wewers, Mark D., Knoell, Daren L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615478/
https://ncbi.nlm.nih.gov/pubmed/23403290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.01.009
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge