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Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBPβ Inhibition

Two vital functions of the innate immune system are to initiate inflammation and redistribute micronutrients in favor of the host. Zinc is an essential micronutrient used in host defense. The zinc importer ZIP8 is uniquely induced through stimulation of the NF-κB pathway by LPS in monocytes and func...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pyle, Charlie J., Akhter, Saife, Bao, ShengYing, Dodd, Claire E., Schlesinger, Larry S., Knoell, Daren L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215883/
https://ncbi.nlm.nih.gov/pubmed/28056086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169531
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