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Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBPβ Inhibition

Two vital functions of the innate immune system are to initiate inflammation and redistribute micronutrients in favor of the host. Zinc is an essential micronutrient used in host defense. The zinc importer ZIP8 is uniquely induced through stimulation of the NF-κB pathway by LPS in monocytes and func...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Pyle, Charlie J., Akhter, Saife, Bao, ShengYing, Dodd, Claire E., Schlesinger, Larry S., Knoell, Daren L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215883/
https://ncbi.nlm.nih.gov/pubmed/28056086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169531
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