Genomic approaches for the discovery of CFTR regulatory elements

Por Ott, Christopher J, Harris, Ann
Publicado em 2011

An insulator element 3′ to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells

Por Blackledge, Neil P., Ott, Christopher J., Gillen, Austin E., Harris, Ann
Publicado em 2009

Interaction of intestinal and pancreatic transcription factors in the regulation of CFTR gene expression

Por McCarthy, Victoria A, Ott, Christopher J, Phylactides, Marios, Harris, Ann
Publicado em 2009

Novel regulatory mechanisms for the CFTR gene

Por Ott, Christopher J., Blackledge, Neil P., Leir, Shih-Hsing, Harris, Ann
Publicado em 2009

Molecular mechanisms controlling CFTR gene expression in the airway

Por Zhang, Zhaolin, Ott, Christopher J, Lewandowska, Marzena A, Leir, Shih-Hsing, Harris, Ann
Publicado em 2012

Cholesterol supplementation during production increases the infectivity of retroviral and lentiviral vectors pseudotyped with the vesicular stomatitis virus glycoprotein (VSV-G)

Por Chen, Yong, Ott, Christopher J., Townsend, Kay, Subbaiah, Papasani, Aiyar, Ashok, Miller, William M.
Publicado em 2009

Spiclypeus shipporum gen. et sp. nov., a Boldly Audacious New Chasmosaurine Ceratopsid (Dinosauria: Ornithischia) from the Judith River Formation (Upper Cretaceous: Campanian) of M...

Por Mallon, Jordan C., Ott, Christopher J., Larson, Peter L., Iuliano, Edward M., Evans, David C.
Publicado no PLoS One (2016)

A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter

Por Ott, Christopher J, Suszko, Magdalena, Blackledge, Neil P, Wright, Jane E, Crawford, Gregory E, Harris, Ann
Publicado em 2009

Nucleosome occupancy reveals regulatory elements of the CFTR promoter

Por Ott, Christopher J., Bischof, Jared M., Unti, Kristen M., Gillen, Austin E., Leir, Shih-Hsing, Harris, Ann
Publicado em 2012

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

Por Ott, Christopher J., Blackledge, Neil P., Kerschner, Jenny L., Leir, Shih-Hsing, Crawford, Gregory E., Cotton, Calvin U., Harris, Ann
Publicado em 2009

The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins

Por Lu, Gang, Middleton, Richard E., Sun, Huahang, Naniong, MarkVic, Ott, Christopher J., Mitsiades, Constantine S., Wong, Kwok-Kin, Bradner, James E., Kaelin, William G.
Publicado em 2013

A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function

Por Bischof, Jared M, Ott, Christopher J, Leir, Shih-Hsing, Gosalia, Nehal, Song, Lingyun, London, Darin, Furey, Terrence S, Cotton, Calvin U, Crawford, Gregory E, Harris, Ann
Publicado em 2011

BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

Por Ott, Christopher J., Kopp, Nadja, Bird, Liat, Paranal, Ronald M., Qi, Jun, Bowman, Teresa, Rodig, Scott J., Kung, Andrew L., Bradner, James E., Weinstock, David M.
Publicado em 2012

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication

Por Koo, Seong Joo, Fernández-Montalván, Amaury E., Badock, Volker, Ott, Christopher J., Holton, Simon J., von Ahsen, Oliver, Toedling, Joern, Vittori, Sarah, Bradner, James E., Gorjánácz, Mátyás
Publicado no Oncotarget (2016)

Nucleosome mapping across the CFTR locus identifies novel regulatory factors

Por Yigit, Erbay, Bischof, Jared M., Zhang, Zhaolin, Ott, Christopher J., Kerschner, Jenny L., Leir, Shih-Hsing, Buitrago-Delgado, Elsy, Zhang, Quanwei, Wang, Ji-Ping Z., Widom, Jonathan, Harris, Ann
Publicado em 2013

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis

Por Viny, Aaron D., Ott, Christopher J., Spitzer, Barbara, Rivas, Martin, Meydan, Cem, Papalexi, Efthymia, Yelin, Dana, Shank, Kaitlyn, Reyes, Jaime, Chiu, April, Romin, Yevgeniy, Boyko, Vitaly, Thota, Swapna, Maciejewski, Jaroslaw P., Melnick, Ari, Bradner, James E., Levine, Ross L.
Publicado no J Exp Med (2015)

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

Por Hogg, Simon J., Vervoort, Stephin J., Deswal, Sumit, Ott, Christopher J., Li, Jason, Cluse, Leonie A., Beavis, Paul A., Darcy, Phillip K., Martin, Benjamin P., Spencer, Andrew, Traunbauer, Anna K., Sadovnik, Irina, Bauer, Karin, Valent, Peter, Bradner, James E., Zuber, Johannes, Shortt, Jake, Johnstone, Ricky W.
Publicado no Cell Rep (2017)

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

Por Winter, Georg E., Mayer, Andreas, Buckley, Dennis L., Erb, Michael A., Roderick, Justine E., Vittori, Sarah, Reyes, Jaime M., di Iulio, Julia, Souza, Amanda, Ott, Christopher J., Roberts, Justin M., Zeid, Rhamy, Scott, Thomas G., Paulk, Joshiawa, Lachance, Kate, Olson, Calla M., Dastjerdi, Shiva, Bauer, Sophie, Lin, Charles Y., Gray, Nathanael S., Kelliher, Michelle A., Churchman, L. Stirling, Bradner, James E.
Publicado no Mol Cell (2017)

An epigenetic mechanism of resistance to targeted therapy in T-cell acute lymphoblastic leukemia

Por Knoechel, Birgit, Roderick, Justine E., Williamson, Kaylyn E., Zhu, Jiang, Lohr, Jens G., Cotton, Matthew J., Gillespie, Shawn M., Fernandez, Daniel, Ku, Manching, Wang, Hongfang, Piccioni, Federica, Silver, Serena J., Jain, Mohit, Pearson, Daniel, Kluk, Michael J., Ott, Christopher J., Shultz, Leonard D., Brehm, Michael A., Greiner, Dale L., Gutierrez, Alejandro, Stegmaier, Kimberly, Kung, Andrew L., Root, David E., Bradner, James E., Aster, Jon C., Kelliher, Michelle A., Bernstein, Bradley E.
Publicado em 2014