A bead-based proximity assay for BRD4 ligand discovery

par Roberts, Justin M., Bradner, James E.
Publié dans Curr Protoc Chem Biol (2015)

Fibroblast growth factors signaling in bone metastasis

par Labanca, Estefania, Vazquez, Elba S, Corn, Paul G, Roberts, Justin M, Wang, Fen, Logothetis, Christopher J, Navone, Nora M
Publié dans Endocr Relat Cancer (2020)

Selective Target Protein Degradation via Phthalimide Conjugation

par Winter, Georg E., Buckley, Dennis L., Paulk, Joshiawa, Roberts, Justin M., Souza, Amanda, Dhe-Paganon, Sirano, Bradner, James E.
Publié dans Science (2015)

The Prostate Cancer TMPRSS2:ERG Fusion Synergizes With the Vitamin D Receptor (VDR) to Induce CYP24A1 Expression-Limiting VDR Signaling

par Kim, Jung-Sun, Roberts, Justin M., Bingman, William E., Shao, Longjiang, Wang, Jianghua, Ittmann, Michael M., Weigel, Nancy L.
Publié dans Endocrinology (2014)

Dynamics of the Tec‐family tyrosine kinase SH3 domains

par Roberts, Justin M., Tarafdar, Sreya, Joseph, Raji E., Andreotti, Amy H., Smithgall, Thomas E., Engen, John R., Wales, Thomas E.
Publié dans Protein Sci (2016)

Synthesis and Biochemical Evaluation of Biotinylated Conjugates of Largazole Analogues: Selective Class I Histone Deacetylase Inhibitors

par Zhao, Le, Dunne, Christine E., Clausen, Dane J., Roberts, Justin M., Paulk, Joshiawa, Liu, Haining, Wiest, Olaf G., Bradner, James E., Williams, Robert M.
Publié dans Isr J Chem (2017)

Design and Characterization of Bivalent BET Inhibitors

par Tanaka, Minoru, Roberts, Justin M., Seo, Hyuk-Soo, Souza, Amanda, Paulk, Joshiawa, Scott, Thomas G., DeAngelo, Stephen L., Dhe-Paganon, Sirano, Bradner, James E.
Publié dans Nat Chem Biol (2016)

Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction

par Condon, Kendall J., Orozco, Jose M., Adelmann, Charles H., Spinelli, Jessica B., van der Helm, Pim W., Roberts, Justin M., Kunchok, Tenzin, Sabatini, David M.
Publié dans Proc Natl Acad Sci U S A (2021)

Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

par Shafi, Ayesha A., Putluri, Vasanta, Arnold, James M., Tsouko, Efrosini, Maity, Suman, Roberts, Justin M., Coarfa, Cristian, Frigo, Daniel E., Putluri, Nagireddy, Sreekumar, Arun, Weigel, Nancy L.
Publié dans Oncotarget (2015)

Vitamin D receptor activation reduces VCaP xenograft tumor growth and counteracts ERG activity despite induction of TMPRSS2:ERG

par Roberts, Justin M., Martin, Rebeca San, Badrajee, D. Piyarathna, MacKrell, James G., Rocha, Guilherme V., Dodge, Jeffery A., Coarfa, Cristian, Krishnan, Venkatesh, Rowley, David R., Weigel, Nancy L.
Publié dans Oncotarget (2017)

A Role for Site-Specific Phosphorylation of Mouse Progesterone Receptor at Serine 191 in Vivo

par Grimm, Sandra L., Ward, Robert D., Obr, Alison E., Franco, Heather L., Fernandez-Valdivia, Rodrigo, Kim, Jung-Sun, Roberts, Justin M., Jeong, Jae-Wook, DeMayo, Francesco J., Lydon, John P., Edwards, Dean P., Weigel, Nancy L.
Publié dans Mol Endocrinol (2014)

The dTAG system for immediate and target-specific protein degradation

par Nabet, Behnam, Roberts, Justin M., Buckley, Dennis L., Paulk, Joshiawa, Dastjerdi, Shiva, Yang, Annan, Leggett, Alan L., Erb, Michael A., Lawlor, Matthew A., Souza, Amanda, Scott, Thomas G., Vittori, Sarah, Perry, Jennifer A., Qi, Jun, Winter, Georg E., Wong, Kwok-Kin, Gray, Nathanael S., Bradner, James E.
Publié dans Nat Chem Biol (2018)

MELK is not necessary for the proliferation of basal-like breast cancer cells

par Huang, Hai-Tsang, Seo, Hyuk-Soo, Zhang, Tinghu, Wang, Yubao, Jiang, Baishan, Li, Qing, Buckley, Dennis L, Nabet, Behnam, Roberts, Justin M, Paulk, Joshiawa, Dastjerdi, Shiva, Winter, Georg E, McLauchlan, Hilary, Moran, Jennifer, Bradner, James E, Eck, Michael J, Dhe-Paganon, Sirano, Zhao, Jean J, Gray, Nathanael S
Publié dans eLife (2017)

Transcription control by the ENL YEATS domain in acute leukemia

par Erb, Michael A., Scott, Thomas G., Li, Bin E., Xie, Huafeng, Paulk, Joshiawa, Seo, Hyuk-Soo, Souza, Amanda, Roberts, Justin M., Dastjerdi, Shiva, Buckley, Dennis L., Sanjana, Neville E., Shalem, Ophir, Nabet, Behnam, Zeid, Rhamy, Offei-Addo, Nana K., Dhe-Paganon, Sirano, Zhang, Feng, Orkin, Stuart H., Winter, Georg E., Bradner, James E.
Publié dans Nature (2017)

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

par Winter, Georg E., Mayer, Andreas, Buckley, Dennis L., Erb, Michael A., Roderick, Justine E., Vittori, Sarah, Reyes, Jaime M., di Iulio, Julia, Souza, Amanda, Ott, Christopher J., Roberts, Justin M., Zeid, Rhamy, Scott, Thomas G., Paulk, Joshiawa, Lachance, Kate, Olson, Calla M., Dastjerdi, Shiva, Bauer, Sophie, Lin, Charles Y., Gray, Nathanael S., Kelliher, Michelle A., Churchman, L. Stirling, Bradner, James E.
Publié dans Mol Cell (2017)

Structural and atropisomeric factors governing the selectivity of pyrimido-benzodiazipinones as inhibitors of kinases and bromodomains

par Wang, Jinhua, Erazo, Tatiana, Ferguson, Fleur M., Buckley, Dennis L., Gomez, Nestor, Muñoz-Guardiola, Pau, Diéguez-Martínez, Nora, Deng, Xianming, Hao, Mingfeng, Massefski, Walter, Fedorov, Oleg, Offei-Addo, Nana Kwaku, Park, Paul M., Dai, Lingling, DiBona, Amy, Becht, Kelly, Kim, Nam Doo, McKeown, Michael R., Roberts, Justin M., Zhang, Jinwei, Sim, Taebo, Alessi, Dario R., Bradner, James E., Lizcano, Jose M., Blacklow, Stephen C., Qi, Jun, Xu, Xiang, Gray, Nathanael S.
Publié dans ACS Chem Biol (2018)

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

par Kalin, Jay H., Wu, Muzhou, Gomez, Andrea V., Song, Yun, Das, Jayanta, Hayward, Dawn, Adejola, Nkosi, Wu, Mingxuan, Panova, Izabela, Chung, Hye Jin, Kim, Edward, Roberts, Holly J., Roberts, Justin M., Prusevich, Polina, Jeliazkov, Jeliazko R., Roy Burman, Shourya S., Fairall, Louise, Milano, Charles, Eroglu, Abdulkerim, Proby, Charlotte M., Dinkova-Kostova, Albena T., Hancock, Wayne W., Gray, Jeffrey J., Bradner, James E., Valente, Sergio, Mai, Antonello, Anders, Nicole M., Rudek, Michelle A., Hu, Yong, Ryu, Byungwoo, Schwabe, John W. R., Mattevi, Andrea, Alani, Rhoda M., Cole, Philip A.
Publié dans Nat Commun (2018)

Response and resistance to BET bromodomain inhibitors in triple negative breast cancer

par Shu, Shaokun, Lin, Charles Y., He, Housheng Hansen, Witwicki, Robert M., Tabassum, Doris P., Roberts, Justin M., Janiszewska, Michalina, Huh, Sung Jin, Liang, Yi, Ryan, Jeremy, Doherty, Ernest, Mohammed, Hisham, Guo, Hao, Stover, Daniel G., Ekram, Muhammad B., Brown, Jonathan, D'Santos, Clive, Krop, Ian E., Dillon, Deborah, McKeown, Michael, Ott, Christopher, Qi, Jun, Ni, Min, Rao, Prakash K., Duarte, Melissa, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Anders, Lars, Young, Richard A., Winer, Eric, Letai, Antony, Barry, William T., Carroll, Jason S., Long, Henry, Brown, Myles, Liu, X. Shirley, Meyer, Clifford A., Bradner, James E., Polyak, Kornelia
Publié dans Nature (2016)